1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Demethoxycurcumin
CAS: 22608-11-3;24939-17-1;33171-16-3
Molecular Formula: C20H18O5
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione - Names and Identifiers
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione - Physico-chemical Properties
| Molecular Formula | C20H18O5 |
| Molar Mass | 338.35 |
| Density | 1.282±0.06 g/cm3(Predicted) |
| Melting Point | 166～170℃ |
| Boling Point | 571.4±50.0 °C(Predicted) |
| Flash Point | 205.5°C |
| Solubility | DMSO : 100 mg/mL (295.55 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble) |
| Vapor Presure | 1.17E-13mmHg at 25°C |
| Appearance | Yellow powder |
| Color | orange |
| pKa | 8.31±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.659 |
| MDL | MFCD03427310 |
| Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Turmeric rhizome. |
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 50 - Very Toxic to aquatic organisms |
| Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 2 |
| HS Code | 29145090 |
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione - Reference
| Reference Show more | 1. Liu Jiahui, Wang Xiujun, Zheng Junhua, et al. Extraction of Curcumin from Guizhou Ginger by Enzymatic-Microwave Method and Its Qualitative Analysis [J]. Preservation and Processing, 2016(3):61-66. 2. Song Shen, Gu Liyun, Xu Jinguo, etc. Study on the Correlation between UFLC-Q-TOF-MS Chromatographic Peak and Inhibition of Tail Thrombosis in Rats before and after Vinegar Preparation of Rhizoma Pariae [J]. Chinese Journal of Traditional Chinese Medicine, Volume 44, Issue 12, 2019, pp. 2511-2518, ISTIC PKU CSCD CA BP, MEDLINE, 2019. 3. [IF = 5.396] Yuan Liang et al."In Vitro and in Silico evaluation of EGFR targeting activities of curcumin and its derivatives." Food Funct. 2021 Nov;12(21):10667-10675 4. [IF = 4.946] Lai Yanni et al."3D-quantitative structure-activity relationship and antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase." Arch Pharm Res. 2020 May;43(5):489-502 5. [IF = 4.821] Le Wang et al."HPLC fingerprint and UV-Vis spectroscopy coupled with chemometrics for Curcumae radix species discrimination and three bioactive compounds prediction." Microchem J. 2021 Jul;166:106254 6. [IF = 4.098] Le Wang et al."Fast discrimination and quantification analysis of Curcumae Radix from four botanical origins using NIR spectroscopy coupled with chemometrics tools." Spectrochim Acta A. 2021 Jun;254:119626 7. [IF = 7.658] Mingyue Zhou et al."Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability." Pharmacol Res. 2022 Mar;:106154 8. [IF = 7.514] Ran Cai et al."Curcumin loading and colon release of pectin gel beans: effect of different de-esterification method." FOOD CHEMISTRY. 2022 Sep;389:133130 |
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione - Reference Information
| biological activity | methoxycurcumin (Demethoxycurcumin) is a major active ingredient of curcumin, which has been proved to have anti-inflammatory and toxic effects on cancer cells. |
| use | demethoxycurcumin has anti-tumor, anti-free radical and lipid-lowering effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: Mainly used to drive hookworm, roundworm, pinworm and mixed infection. Toosendanin is an effective component of the skin of neem. It has a stronger effect than ethanol extract. Compared with Shan Daonen, the effect is slow and long. Toosendanin has an inhibitory effect on the respiratory center. |
Last Update：2024-04-09 20:52:54
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Product Name: Demethoxycurcumin Visit Supplier Webpage Request for quotationCAS: 22608-11-3
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Demethoxycurcumin Visit Supplier Webpage Request for quotationCAS: 22608-11-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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