1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE
tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate
CAS: 77279-24-4
Molecular Formula: C11H22N2O3
1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE - Names and Identifiers
1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE - Physico-chemical Properties
| Molecular Formula | C11H22N2O3 |
| Molar Mass | 230.3 |
| Density | 1.092±0.06 g/cm3(Predicted) |
| Melting Point | 38-42 °C |
| Boling Point | 114°C 0,1mm |
| Flash Point | 110°C |
| Appearance | Solid |
| Color | White to pale brown |
| pKa | 14.96±0.10(Predicted) |
| Storage Condition | 2-8°C |
1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R25 - Toxic if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE - Introduction
tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate, the chemical formula is C13H26N2O3, is an organic compound.
Nature:
-Appearance: Colorless or light yellow liquid or solid.
-Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-Melting point: about 30-40 degrees Celsius.
-Stability: Stable at room temperature.
Use:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be used as a synthetic drug intermediate for the preparation of many drugs, such as antipsychotics, antidepressants and antiemetic drugs.
Preparation Method:
The preparation method of tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be obtained by the following steps:
1. First, tert-butyl chloroformate is reacted with 2-hydroxyethyl piperazine to generate tert-butyl -4-(2-hydroxyethyl) piperazine.
2. Then, in the presence of a base, it reacts with chloroformic acid to generate the tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate.
Safety Information:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate is an organic compound and will not directly cause harm to the human body under normal circumstances.
-During use, it is recommended to follow chemical safety practices, such as wearing protective gloves, glasses and laboratory coats.
-In case of swallowing or skin contact, flush with plenty of water and seek medical help.
Nature:
-Appearance: Colorless or light yellow liquid or solid.
-Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-Melting point: about 30-40 degrees Celsius.
-Stability: Stable at room temperature.
Use:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be used as a synthetic drug intermediate for the preparation of many drugs, such as antipsychotics, antidepressants and antiemetic drugs.
Preparation Method:
The preparation method of tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be obtained by the following steps:
1. First, tert-butyl chloroformate is reacted with 2-hydroxyethyl piperazine to generate tert-butyl -4-(2-hydroxyethyl) piperazine.
2. Then, in the presence of a base, it reacts with chloroformic acid to generate the tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate.
Safety Information:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate is an organic compound and will not directly cause harm to the human body under normal circumstances.
-During use, it is recommended to follow chemical safety practices, such as wearing protective gloves, glasses and laboratory coats.
-In case of swallowing or skin contact, flush with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54
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Product Name: Tert-Butyl 4-(2-Hydroxyethyl)Piperazine-1-Carboxylate Visit Supplier Webpage Request for quotationCAS: 77279-24-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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