BOC-N-(2-HYDROXYETHYL)PIPERAZINE - Names and Identifiers
BOC-N-(2-HYDROXYETHYL)PIPERAZINE - Physico-chemical Properties
Molecular Formula | C11H22N2O3
|
Molar Mass | 230.3 |
Density | 1.092±0.06 g/cm3(Predicted) |
Melting Point | 38-42 °C |
Boling Point | 114°C 0,1mm |
Flash Point | 110°C |
Appearance | Solid |
Color | White to pale brown |
pKa | 14.96±0.10(Predicted) |
Storage Condition | 2-8°C |
BOC-N-(2-HYDROXYETHYL)PIPERAZINE - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R50 - Very Toxic to aquatic organisms
R25 - Toxic if swallowed
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
Hazard Note | Irritant |
Hazard Class | 6.1 |
Packing Group | Ⅲ |
BOC-N-(2-HYDROXYETHYL)PIPERAZINE - Introduction
tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate, the chemical formula is C13H26N2O3, is an organic compound.
Nature:
-Appearance: Colorless or light yellow liquid or solid.
-Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-Melting point: about 30-40 degrees Celsius.
-Stability: Stable at room temperature.
Use:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be used as a synthetic drug intermediate for the preparation of many drugs, such as antipsychotics, antidepressants and antiemetic drugs.
Preparation Method:
The preparation method of tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate can be obtained by the following steps:
1. First, tert-butyl chloroformate is reacted with 2-hydroxyethyl piperazine to generate tert-butyl -4-(2-hydroxyethyl) piperazine.
2. Then, in the presence of a base, it reacts with chloroformic acid to generate the tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate.
Safety Information:
- tert-Butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate is an organic compound and will not directly cause harm to the human body under normal circumstances.
-During use, it is recommended to follow chemical safety practices, such as wearing protective gloves, glasses and laboratory coats.
-In case of swallowing or skin contact, flush with plenty of water and seek medical help.
Last Update:2024-04-09 21:01:54