1110782-41-6

1110782-41-6 - Names and Identifiers

Name	3-Pyridinecarboxylic acid, 6-chloro-5-(trifluoromethyl)-
Synonyms	6-Chloro-5-(trifluoromethyl)nicotinic acid 6-Chloro-5-(trifluoromethyl)pyridine-3-carboxylic acid 6-Chloro-5-(trifluoromethyl)-3-pyridinecarboxylic acid 2-Chloro-3-(trifluoromethyl)pyridine-5-carboxylic acid 6-chloro-5-(trifluoromethyl)pyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 6-chloro-5-(trifluoroMethyl)- 3-Pyridinecarboxylic acid, 6-chloro-5-(trifluoromethyl)- 6-Chloro-5-(trifluoromethyl)pyridine-3-carboxylic acid, 5-Carboxy-2-chloro-3-(trifluoromethyl)pyridine
CAS	1110782-41-6

1110782-41-6 - Physico-chemical Properties

Molecular Formula	C7H3ClF3NO2
Molar Mass	225.55
Density	1.603±0.06 g/cm3(Predicted)
Boling Point	323.3±42.0 °C(Predicted)
pKa	2.81±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	IRRITANT
MDL	MFCD11848376

1110782-41-6 - Risk and Safety

Hazard Class

IRRITANT

1110782-41-6 - Introduction

2-Chloro-3-trifluoromethylpyridine-5-carboxylic acid, also known as CF3CPyCOOH, is an organic compound.

Nature:
-Appearance: colorless liquid
-Molecular formula: C7H3ClF3NO2
-Molecular Weight: 233.5
-Solubility: Soluble in organic solvents such as methanol, ethanol and dimethylformamide
-melting point and boiling point: there is no public data for reference

Use:
-2-Chloro-3-trifluoromethylpyridine-5-carboxylic acid is usually used as a reagent in organic synthesis, and is particularly suitable for reactions in the presence of metal catalysts.
-It can be used as a precursor for the synthesis of fluorine-containing compounds and has an important impact on the synthesis of many drugs and pesticides.

Preparation Method:
The preparation method of 2-chloro-3-trifluoromethylpyridine-5-carboxylic acid is complicated. One common method of preparation is by reacting 3-trifluoromethylpyridine with chlorine gas to give 2,3-dichloro-5-trifluoromethylpyridine. Then, the resulting product is reacted with silver oxide and then with copper nitrite to finally obtain 2-chloro-3-trifluoromethylpyridine-5-carboxylic acid.

Safety Information:
-2-Chloro-3-trifluoromethylpyridine-5-carboxylic acid should be kept away from heat sources and open flames during storage and use to prevent contact with oxidants and avoid hazardous substances.
-Wear protective gloves, goggles and respiratory protection when used.
-Ensure a well-ventilated laboratory environment during use.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When handling the compound, the relevant safety procedures and regulations should be strictly observed.

Last Update：2024-04-09 15:17:50