113451-59-5

113451-59-5 - Names and Identifiers

Name	(1S,4S)-2-BOC-2,5-diazabicyclo(2.2.1)heptane
Synonyms	(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane (1S,4S)-2-BOC-2,5-diazabicyclo(2.2.1)heptane (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (1S,4S)-N-BOC-2,5-DIAZA-BICYCLO[2.2.1]HEPTANE (1S,4S)-2-T-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (1S,4S)-(-)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (1S,4S)-2-N-T-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane N-(tert-Butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptane tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate (1S,4S)-N-(TERT-BUTOXYCARBONYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-carboxylate TERT-BUTYL (1S,4S)-2,5-DIAZABICYCLO(2.2.1)HEPTANE-2-CARBOXYLATE tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate tert.-Butyl (1S,4S)-2,5-diazabicyclo(2.2.1)heptane-2-carboxylate TERT-BUTYL (1S, 4S)-(-)-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE 1,1-Dimethylethyl (1S,4S)-2,5-diazabicyclo(2.2.1)heptane-2-carboxylate (1S,4S)-2-t-Boc-2,5-diazabicyclo(1S,4S)-2-t-Boc-2,5-diazabicyclo[2.2.1]heptane
CAS	113451-59-5
EINECS	674-133-3
InChI	InChI=1/C10H18N2O2/c1-10(2,3)14-9(13)12-6-7-4-8(12)5-11-7/h7-8,11H,4-6H2,1-3H3/t7-,8-/m0/s1

113451-59-5 - Physico-chemical Properties

Molecular Formula	C10H18N2O2
Molar Mass	198.26
Density	1.104±0.06 g/cm3(Predicted)
Melting Point	74-76°C(lit.)
Boling Point	276.4±15.0 °C(Predicted)
Specific Rotation(α)	-44o (C=1 IN CHLOROFORM)
Flash Point	120.946°C
Water Solubility	Insoluble in water.
Vapor Presure	0.005mmHg at 25°C
Appearance	White to light beige powder or crystal
Color	White to slightly beige
BRN	6460311
pKa	9.74±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Sensitive	Air Sensitive
Refractive Index	1.501
MDL	MFCD01569250

113451-59-5 - Risk and Safety

Risk Codes	34 - Causes burns
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	3263
WGK Germany	3
HS Code	29335990

113451-59-5 - Introduction

(1S,4S)-2-Boc-2, 5-diazobicyclo [2.2.1] heptane, is an organic compound. Its molecular formula is C14H25NO2 and its molecular weight is 247.35g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
(1S,4S)-2-Boc-2, 5-diazobicyclo [2.2.1] heptane is a colorless to light yellow solid with a special ring structure. It is insoluble in water, but can be dissolved in some organic solvents, such as methanol, ethanol and ether solvents. It is stable at room temperature, but should avoid direct sunlight.

Use:
The compound is commonly used as an intermediate in organic synthesis. It can be used as a chiral inducer for the synthesis of chiral compounds. Due to the particularity of its ring structure, it has unique reactivity in some chemical reactions, so it is widely used in the field of organic synthesis.

Preparation Method:
The preparation of (1S,4S)-2-Boc-2, 5-diazobicyclo [2.2.1] heptane usually involves a multi-step reaction. A common preparation method is to synthesize a known compound, for example, by carrying out an ortho nucleophilic substitution reaction on cycloheptanone to form the corresponding cycloheptyl compound, and then introduce a protecting group (Boc) into it by a suitable reaction step.

Safety Information:
When using (1S,4S)-2-Boc-2, 5-diazobicyclo [2.2.1] heptane, some safety precautions need to be paid attention. Because it is an organic compound, it may be toxic and irritating to the human body. During operation, it is recommended to wear appropriate protective gloves, glasses and protective clothing. Avoid inhaling its vapor or dust, and ensure that it is operated in a well-ventilated place. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool place and avoid contact with strong oxidants or strong acids.

Last Update：2024-04-10 22:29:15