114248-23-6

114248-23-6 - Names and Identifiers

Name	2',2'-DIFLUORO-2'-DEOXYURIDINE
Synonyms	Gemcitabine Metabolite 2Deoxy-22difluorouridine 2',2'-Difluorodeoxyuridine 2'-Deoxy-2,2'difluorouridine 2',2'-DIFLUORO-2'-DEOXYURIDINE Uridine,2'-deoxy-2',2'-difluoro- 2'-Deoxy-2',2'-difluoro-D-uridine 2'-deoxy-2',2'-fluorouracil nucleoside
CAS	114248-23-6
InChI	InChI=1/C9H10F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h1-2,4,6-7,14,16H,3H2,(H,12,15,17)/t4-,6+,7-/m1/s1
InChIKey	FIRDBEQIJQERSE-PRMYIZFSSA-N

114248-23-6 - Physico-chemical Properties

Molecular Formula	C9H10F2N2O5
Molar Mass	264.18
Density	1.69±0.1 g/cm3(Predicted)
Melting Point	147-149°C
Solubility	Methanol (Slightly), Water (Very Slightly, Heated)
Appearance	Solid
Color	White to Off-White
pKa	9.39±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.587

114248-23-6 - Risk and Safety

HS Code

29389090

114248-23-6 - Introduction

2 '-deoxy-2',2 '-difluorouracil nucleoside is a chemical, also known as ddUTP. The following is a description of its nature, use, preparation and safety information:

Nature:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is a white crystalline powder.
-Its chemical formula is C9H13N2O11P2F2, and its relative molecular mass is 406.16g/mol.
-Low solubility at room temperature and can be dissolved in water.
-It is a nucleotide similar to uracil, but the hydrogen atoms at the 2 'and 2 "positions are replaced by fluorine atoms.

Use:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is an important biotechnological reagent.
-It is commonly used in DNA sequencing and DNA synthesis as a chain terminator.
-In molecular biology, it can be used to detect and quantify specific DNA sequences.

Method:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is prepared by various methods.
-A commonly used method is to synthesize this nucleotide through chemical synthesis.

Safety Information:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is generally relatively safe under proper use and storage conditions.
-But because it is a chemical substance, it still needs to be used with caution.
-When using, please follow laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-It should be stored in a dry, cool place, away from fire and flammable substances.

Please note that when using or handling any chemical substances, please always follow laboratory safety regulations and consult professionals as needed.

Last Update：2024-04-10 22:29:15