2Deoxy-22difluorouridine
2',2'-DIFLUORO-2'-DEOXYURIDINE
CAS: 114248-23-6
Molecular Formula: C9H10F2N2O5
2Deoxy-22difluorouridine - Names and Identifiers
| Name | 2',2'-DIFLUORO-2'-DEOXYURIDINE |
| Synonyms | Gemcitabine Metabolite 2Deoxy-22difluorouridine 2',2'-Difluorodeoxyuridine 2'-Deoxy-2,2'difluorouridine 2',2'-DIFLUORO-2'-DEOXYURIDINE Uridine,2'-deoxy-2',2'-difluoro- 2'-Deoxy-2',2'-difluoro-D-uridine 2'-deoxy-2',2'-fluorouracil nucleoside |
| CAS | 114248-23-6 |
| InChI | InChI=1/C9H10F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h1-2,4,6-7,14,16H,3H2,(H,12,15,17)/t4-,6+,7-/m1/s1 |
| InChIKey | FIRDBEQIJQERSE-PRMYIZFSSA-N |
2Deoxy-22difluorouridine - Physico-chemical Properties
| Molecular Formula | C9H10F2N2O5 |
| Molar Mass | 264.18 |
| Density | 1.69±0.1 g/cm3(Predicted) |
| Melting Point | 147-149°C |
| Solubility | Methanol (Slightly), Water (Very Slightly, Heated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 9.39±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.587 |
2Deoxy-22difluorouridine - Risk and Safety
| HS Code | 29389090 |
2Deoxy-22difluorouridine - Introduction
2 '-deoxy-2',2 '-difluorouracil nucleoside is a chemical, also known as ddUTP. The following is a description of its nature, use, preparation and safety information:
Nature:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is a white crystalline powder.
-Its chemical formula is C9H13N2O11P2F2, and its relative molecular mass is 406.16g/mol.
-Low solubility at room temperature and can be dissolved in water.
-It is a nucleotide similar to uracil, but the hydrogen atoms at the 2 'and 2 "positions are replaced by fluorine atoms.
Use:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is an important biotechnological reagent.
-It is commonly used in DNA sequencing and DNA synthesis as a chain terminator.
-In molecular biology, it can be used to detect and quantify specific DNA sequences.
Method:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is prepared by various methods.
-A commonly used method is to synthesize this nucleotide through chemical synthesis.
Safety Information:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is generally relatively safe under proper use and storage conditions.
-But because it is a chemical substance, it still needs to be used with caution.
-When using, please follow laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-It should be stored in a dry, cool place, away from fire and flammable substances.
Please note that when using or handling any chemical substances, please always follow laboratory safety regulations and consult professionals as needed.
Nature:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is a white crystalline powder.
-Its chemical formula is C9H13N2O11P2F2, and its relative molecular mass is 406.16g/mol.
-Low solubility at room temperature and can be dissolved in water.
-It is a nucleotide similar to uracil, but the hydrogen atoms at the 2 'and 2 "positions are replaced by fluorine atoms.
Use:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is an important biotechnological reagent.
-It is commonly used in DNA sequencing and DNA synthesis as a chain terminator.
-In molecular biology, it can be used to detect and quantify specific DNA sequences.
Method:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is prepared by various methods.
-A commonly used method is to synthesize this nucleotide through chemical synthesis.
Safety Information:
- 2 '-deoxy-2',2 '-difluorouracil nucleoside is generally relatively safe under proper use and storage conditions.
-But because it is a chemical substance, it still needs to be used with caution.
-When using, please follow laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-It should be stored in a dry, cool place, away from fire and flammable substances.
Please note that when using or handling any chemical substances, please always follow laboratory safety regulations and consult professionals as needed.
Last Update：2024-04-10 22:29:15
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View History
2Deoxy-22difluorouridine
1,2,3-Propanetriol, 2-methyl-, 1-(4-methylbenzenesulfonate), (S)- (9CI)
Tegin G
19089-92-0
4-(1-Methylethyl)benzonitrile
Ritainic Acid
2-Hydrazinobenzothiazole
2,3-Dimethyl-2-butenoic acid (2E)-3,7-dimethyl-2,6-octadienyl ester
Methylic Ether
Propionic acid, 2-((4-chloro-o-tolyl)oxy)-, methyl ester
1,2,3-Propanetriol, 2-methyl-, 1-(4-methylbenzenesulfonate), (S)- (9CI)
Tegin G
19089-92-0
4-(1-Methylethyl)benzonitrile
Ritainic Acid
2-Hydrazinobenzothiazole
2,3-Dimethyl-2-butenoic acid (2E)-3,7-dimethyl-2,6-octadienyl ester
Methylic Ether
Propionic acid, 2-((4-chloro-o-tolyl)oxy)-, methyl ester