1174309-16-0 - Names and Identifiers
1174309-16-0 - Physico-chemical Properties
Molecular Formula | C4H5F2N3
|
Molar Mass | 133.0994064 |
Density | 1.54±0.1 g/cm3(Predicted) |
Boling Point | 214.4±40.0 °C(Predicted) |
pKa | 2.59±0.15(Predicted) |
Storage Condition | Room Temprature |
1174309-16-0 - Upstream Downstream Industry
1174309-16-0 - Introduction
1-(difluoromethyl)-1h-pyrazol-4-amine(1-(difluoromethyl)-1H-pyrazol-4-amine) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually a colorless crystalline solid.
-chemical formula: C4H4F2N4
-Molecular weight: 146.10g/mol
-Melting Point: 148-152 ℃
-Boiling point: About 351 ℃
-Solubility: It can be dissolved in many organic solvents at room temperature, such as ethanol, methanol and dichloromethane.
Use:
1-(difluoromethyl)-1h-pyrazol-4-amine can be used in many reactions for the synthesis of organic compounds, including the synthesis of drugs and pesticides. It can also be used as a catalyst or intermediate.
Method:
1-(difluoromethyl)-1h-pyrazol-4-amine can be prepared by the following steps:
1. First, the reaction of methyl isocyanate (methyl isocyanate) with sodium difluoromethylformate (sodium difluoromethanide) generates methyl 1-difluoromethylpyrazole formate.
2. Then, under alkaline conditions, 1-difluoromethylpyrazole methyl carboxylate was treated with ammonia water to produce 1-(difluoromethyl)-1h-pyrazol-4-amine.
Safety Information:
The safety of the 1-(difluoromethyl)-1h-pyrazol-4-amine compound has not been fully established. It may be harmful to human health and irritating. When handling and handling, should follow the relevant safety procedures, wear protective gloves and safety glasses. It is recommended to operate in a well-ventilated place and avoid direct contact with the skin and inhalation of dust or steam. In case of accidental contact or inhalation, seek medical attention immediately.
Last Update:2024-04-09 21:01:54