1223044-18-5

1223044-18-5 - Names and Identifiers

Name	6-Phenylhexyldimethyl(Dimethylamino)Silane
Synonyms	6-PHENYLHEXYLDIMETHYL(DIMETHYLAMINO)SILANE 6-Phenylhexyldimethyl(Dimethylamino)Silane Silanamine, N,N,1,1-tetramethyl-1-(6-phenylhexyl)-
CAS	1223044-18-5

1223044-18-5 - Physico-chemical Properties

Molecular Formula	C16H29NSi
Molar Mass	263.49
Density	0.886±0.06 g/cm3(Predicted)
Boling Point	120°C / 0.5
pKa	9.89±0.70(Predicted)
Sensitive	8: reacts rapidly with moisture, water, protic solvents

1223044-18-5 - Introduction

6-Phenyl-hexyldimethyl (dimethylamino) silane, PhHMDS for short, is an organosilicon compound. The following is a description of the nature, use, preparation and safety information of PhHMDS:

Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C16H25NSi
-Molecular weight: 271.46g/mol
-melting point: peak at about -11 ℃
-Boiling point: 68-70 ℃/0.3mmHg
-Density: 0.873g/cm³
-Solubility: Soluble in common organic solvents

Use:
PhHMDS is widely used in the field of organic chemistry, especially as a catalyst for strong alkali agents and silicon sources. It has the following main uses:
-Strong alkaline agent: PhHMDS can be used as a non-aqueous alkaline agent for deprotonation and alkaline reagents.
-Highly active metal silane reagents: PhHMDS can be reacted with metal halides to prepare highly active metal silane reagents, such as aluminum silane and zinc silane, catalysts for organic synthesis reactions.
-Deblocking agent: PhHMDS can be used for deblocking reactions in organic synthesis processes.

Preparation Method:
The preparation of PhHMDS is generally carried out by the following steps:
1. the reaction of hexyl aluminum bromide and phenyl red blue to generate 6-hexyl benzene.
2. 6-hexylbenzene reacts with dimethylchlorosilane to generate 6-hexyl-dimethylchlorosilane.
3. Finally, 6-hexyl-dimethylchlorosilane is reacted with dimethylaniline to produce PhHMDS.

Safety Information:
When using PhHMDS, you need to pay attention to the following safety precautions:
-Avoid contact with skin, eyes and respiratory tract. Wear gloves, goggles and a mask when using.
-Use in a well-ventilated place to avoid prolonged exposure indoors.
-Avoid contact with oxygen and moisture during storage to avoid dangerous reactions.
-If you have been exposed to PhHMDS, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15