130064-21-0

130064-21-0 - Names and Identifiers

Name	1,2-(2'-Hydroxyl-4',4'-bis-alpha-pyranol)diphenylethanone
Synonyms	1-[2-Hydroxy-4-[(tetrahydro-2H-pyran-2-yl)oxy] 1,2-(2'-Hydroxyl-4',4'-bis-alpha-pyranol)diphenylethanone 1,2-(2'-Hydroxyl-4',4''-Bis-Alpha-Pyranol)Diphenylethanone 1,2-(2'-Hydroxyl-4',4''-bis-alpha-pyranol)diphenylethanone 1-[2-hydroxy-4-(oxan-2-yloxy)phenyl]-2-[4-(oxan-2-yloxy)phenyl]ethanone 1-[2-Hydroxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]ethanone 1-(2-hydroxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethan-1-one Ethanone, 1-[2-hydroxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-
CAS	130064-21-0

130064-21-0 - Physico-chemical Properties

Molecular Formula	C24H28O6
Molar Mass	412.48
Density	1.230
Melting Point	118 °C(Solv: hexane (110-54-3))
Boling Point	613.3±55.0 °C(Predicted)
pKa	7.34±0.35(Predicted)
Storage Condition	2-8°C

130064-21-0 - Introduction

1,2-(2 '-Hydroxy-4',4 '-di-alpha-pyranol) diphenyl ethanone, often abbreviated as 2,4'-Dihydroxyacetophenone, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2,4 '-Dihydroxyacetophenone are colorless crystals or white solids.
-Solubility: Its solubility in water is low, but it has a certain degree of solubility in most organic solvents.
-Melting point: 132-135°C
-Thermal stability: The compound is relatively stable and is not easy to decompose at normal temperature.

Use:
-Drug synthesis: 2,4 '-Dihydroxyacetophenone can be used as an intermediate for the preparation of a variety of drugs and bioactive molecules.
-Cosmetics: Because of its antioxidant and anti-inflammatory effects, it is also used in cosmetics and skin care products.
-Food additive: It is used as an antioxidant and preservative in some foods.

Preparation Method:
The preparation method of 2,4 '-Dihydroxyacetophenone can be carried out by a two-step method of hydroxylation synthesis and ketone acetophenone synthesis.
-hydroxylation synthesis: first, 2-hydroxyacetophenone is synthesized, acetophenone is generated by the reaction of benzaldehyde and sodium hydroxide, and then 2-hydroxyacetophenone is synthesized by acid-catalyzed aldol reaction.
-ketoacetophenone synthesis: 2-hydroxyacetophenone was reacted with ethyl methyl acetoacetate under alkali catalysis to obtain 1,2-(2 '-hydroxy -4',4 '-di-alpha-pyranol) diphenyl ethyl ketone.

Safety Information:
- 2,4 '-Dihydroxyacetophenone is generally safe under reasonable use conditions, but the following matters still need to be paid attention:
-Contact: Avoid direct contact, wear gloves, goggles and appropriate protective clothing.
-Inhalation: Work in a well-ventilated place to avoid inhaling dust and vapor.
-Edible: The compound should not be used in food or for direct ingestion and should only be used for suitable industrial or laboratory purposes.

Please note that the above information is for reference only, and the specific use and treatment should be carried out according to the actual situation. It is strongly recommended to carefully read and follow the safety instructions for the substance in question before use.

Last Update：2024-04-09 15:17:51