139115-92-7

139115-92-7 - Names and Identifiers

Name	(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER
Synonyms	BocNH-PEG3-OH NHBoc-PEG3-OH 2-[2-[2-T-BOC-AMINOETHOXY]ETHOXY]ETHANOL 2-[2-[2-(Boc-amino)ethoxy]ethoxy]ethanol 2-[2-(2-tert-ButyloxycarbonylaMinoethoxy)ethoxy]ethanol tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbaMate (2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER N-[2-[2-(2-Hydroxyethoxy)ethoxy]ethyl]carbaMic Acid 1,1-DiMethylethyl Ester
CAS	139115-92-7

139115-92-7 - Physico-chemical Properties

Molecular Formula	C11H23NO5
Molar Mass	249.304
Density	1.071±0.06 g/cm3(Predicted)
Boling Point	374.6±27.0 °C(Predicted)
pKa	12.22±0.46(Predicted)
Storage Condition	Sealed in dry,2-8°C
Stability	Light and Moisture Sensitive
Use	Application 2-[2-(2-T-BOC-aminoethoxy) ethoxy] Ethanol is an organic intermediate and pharmaceutical intermediate, which can be used in laboratory research and development process and chemical and pharmaceutical synthesis process, it can be prepared from triethylene glycol by a three-step reaction. 2-[2-(2-T-BOC-aminoethoxy) ethoxy] Ethanol is often used as Linker in organic compounds.

139115-92-7 - Upstream Downstream Industry

Downstream Products

2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
t-Boc-N-Amido-PEG3-propargyl
2-[2-(2-Azidoethoxy)ethoxy]ethanamine

139115-92-7 - Introduction

(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER is a compound with the following properties:

1. Appearance: colorless or yellowish liquid.
2. Molecular formula: C14H27NO5.
3. Molecular weight: 289.37g/mol.
4. Melting Point: below room temperature.
5. Boiling point: About 300 ° C.
6. Solubility: Soluble in organic solvents such as dichloromethane, diethyl ether and dimethylformamide.

This compound is commonly used in protecting group reactions in the field of organic synthesis. Its specific uses are as follows:

1. Used as an amino protecting group:(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER can be used as an amino protecting group and play the role of protecting amino in organic synthesis, to prevent undesired reactions during the reaction.
2. Used in synthetic drugs: It can also be used in synthetic drugs, natural products and other organic compounds to provide protection or adjust the reaction process.

(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER can be prepared by the following steps:

1. Reaction raw materials: Ethylene Glycol, dimethyl carbamate (DMT-MM), BOC-aminoethanol, butoxy particles, anhydrous tetrahydrofuran (THF), etc.
2. Reaction step: mix ethylene glycol, DMT-MM and anhydrous THF, add butoxy particles, then BOC-aminoethanol, and react at an appropriate temperature.
3. Separation and purification: After the reaction, the target product can be obtained by suitable separation and purification methods (such as solvent extraction, crystallization, etc.).

Regarding safety information,(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER is a chemical, so you need to pay attention to the following:

1. Avoid inhalation: avoid inhalation of compounds of dust, gas or vapor, should be in a well ventilated place of operation.
2. Avoid contact with eyes and skin: Flush eyes or skin immediately with plenty of water and seek medical attention.
3. Storage Note: It should be stored in a cool, dry and well-ventilated place, away from fire and combustibles.

When using and handling, please follow the safe handling procedures for chemicals, and take appropriate protective measures, such as wearing gloves, goggles and protective clothing.

Last Update：2024-04-09 21:21:28