1483-54-1 - Names and Identifiers
1483-54-1 - Physico-chemical Properties
Molecular Formula | C8H5F3N2
|
Molar Mass | 186.13 |
Density | 1.37±0.1 g/cm3(Predicted) |
Melting Point | 88.0 to 92.0 °C |
Boling Point | 127°C/7mmHg(lit.) |
Flash Point | 120.8°C |
Vapor Presure | 0.0049mmHg at 25°C |
Appearance | powder to crystalline |
Color | White to Light yellow |
pKa | 0.59±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.499 |
1483-54-1 - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
UN IDs | UN 3439 6.1/PG III |
HS Code | 29269090 |
Hazard Class | 6.1 |
Packing Group | III |
1483-54-1 - Introduction
2-amino-4-(trifluoromethyl) benzontrile is an organic compound with the chemical formula C8H5F3N. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
1. Appearance: colorless or light yellow solid.
2. Melting Point: about 46-49 ℃.
3. Boiling point: About 240 ℃.
4. Solubility: Soluble in organic solvents, such as methanol, ethanol and dimethylformamide.
Use:
1. 2-amino-4-(trifluoromethyl)benzonitril is commonly used as an intermediate of some drugs. It can be used for the synthesis of peptide drugs, hormone drugs and anti-tumor drugs.
2. The compound can also be used as a synthetic intermediate for dyes and has a wide range of applications in the dye industry.
Method:
The preparation of 2-amino-4-(trifluoromethyl) benzonite can be carried out by the following steps:
1. The reaction of 2-amino -4-methyl nitrobenzene nitrile with trifluoromethyl sulfide is carried out under alkaline conditions.
2. After the reaction is completed, the product is obtained by treatment with hydrochloric acid.
Safety Information:
1. 2-amino-4-(trifluoromethyl)benzonitril is an organic compound and should comply with regular chemical laboratory safety procedures.
2. Prohibit direct contact with skin and eyes, cause irritation and burns.
3. The specific safe operation and treatment methods should be evaluated and adopted according to different application fields and uses. Recommended for use under professional guidance.
Last Update:2024-04-09 15:17:52