3-AMINO-4-CYANOBENZOTRIFLUORIDE

3-AMINO-4-CYANOBENZOTRIFLUORIDE - Names and Identifiers

Name	2-amino-4-(trifluoromethyl)benzonitrile
Synonyms	3-AMINO-4-CYANOBENZOTRIFLUORIDE 2-Amino-4-(trifluoromethyl)benzotrile 2-Amino-4-trifluoromethylbenzonitrile 2-AMINO-4-(TRIFLUOROMETHYL)BENZONITRILE 2-amino-4-(trifluoromethyl)benzonitrile Benzonitrile, 2-amino-4-(trifluoromethyl)- 2-azanyl-3-(trifluoromethyl)benzenecarbonitrile 2-Cyano-5-(trifluoromethyl)aniline, 2-Amino-4-(trifluoromet 2-Cyano-5-(trifluoromethyl)aniline, 2-Amino-4-(trifluoromethyl)benzonitrile
CAS	1483-54-1
EINECS	216-047-7
InChI	InChI=1/C8H5F3N2/c9-8(10,11)6-2-1-5(4-12)7(13)3-6/h1-3H,13H2

3-AMINO-4-CYANOBENZOTRIFLUORIDE - Physico-chemical Properties

Molecular Formula	C8H5F3N2
Molar Mass	186.13
Density	1.37±0.1 g/cm3(Predicted)
Melting Point	88.0 to 92.0 °C
Boling Point	127°C/7mmHg(lit.)
Flash Point	120.8°C
Vapor Presure	0.0049mmHg at 25°C
Appearance	powder to crystalline
Color	White to Light yellow
pKa	0.59±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.499

3-AMINO-4-CYANOBENZOTRIFLUORIDE - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 3439 6.1/PG III
HS Code	29269090
Hazard Class	6.1
Packing Group	III

3-AMINO-4-CYANOBENZOTRIFLUORIDE - Introduction

2-amino-4-(trifluoromethyl) benzontrile is an organic compound with the chemical formula C8H5F3N. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
1. Appearance: colorless or light yellow solid.
2. Melting Point: about 46-49 ℃.
3. Boiling point: About 240 ℃.
4. Solubility: Soluble in organic solvents, such as methanol, ethanol and dimethylformamide.

Use:
1. 2-amino-4-(trifluoromethyl)benzonitril is commonly used as an intermediate of some drugs. It can be used for the synthesis of peptide drugs, hormone drugs and anti-tumor drugs.
2. The compound can also be used as a synthetic intermediate for dyes and has a wide range of applications in the dye industry.

Method:
The preparation of 2-amino-4-(trifluoromethyl) benzonite can be carried out by the following steps:
1. The reaction of 2-amino -4-methyl nitrobenzene nitrile with trifluoromethyl sulfide is carried out under alkaline conditions.
2. After the reaction is completed, the product is obtained by treatment with hydrochloric acid.

Safety Information:
1. 2-amino-4-(trifluoromethyl)benzonitril is an organic compound and should comply with regular chemical laboratory safety procedures.
2. Prohibit direct contact with skin and eyes, cause irritation and burns.
3. The specific safe operation and treatment methods should be evaluated and adopted according to different application fields and uses. Recommended for use under professional guidance.

Last Update：2024-04-09 15:17:52