16990-73-1 - Names and Identifiers
16990-73-1 - Physico-chemical Properties
Molecular Formula | C8H7NO
|
Molar Mass | 133.15 |
Density | 1.327g/cm3 |
Boling Point | 343.2°C at 760 mmHg |
Flash Point | 161.4°C |
Vapor Presure | 3.61E-05mmHg at 25°C |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.739 |
16990-73-1 - Introduction
1H-indol-2-ol, also known as 2-hydroxymethylindole, is an organic compound. Its chemical formula is C9H9NO and has a molecular weight of 159.17g/mol. The following is a description of its nature, use, preparation and safety information:
Properties: 1H-indol-2-ol is a white to light yellow crystalline solid with a special indole ring structure and a hydroxymethyl functional group. It is soluble in polar solvents such as water, ethanol and chloroform.
Application: 1H-indol-2-ol has certain application value in medicinal chemistry. It can be used as a synthetic intermediate of alkaloids and is used to prepare a variety of drugs, such as antipsychotic drugs chlorimipramine, sodium phytate and so on. In addition, it can also be used to synthesize pesticides, pigments and dyes.
Preparation method: 1H-indol-2-ol can be prepared by a variety of methods, the most commonly used method is obtained by the condensation reaction of indole and formaldehyde. Under alkaline conditions, indole and formaldehyde react to produce the corresponding aldehyde condensate, which is then reduced to give 1H-indol-2-ol.
Safety Information: 1H-indol-2-ol is generally considered to be a low-toxic compound, but correct safe handling procedures must be followed. During the operation should maintain good ventilation, avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, in accordance with local regulations and regulations, the compound needs to be stored and handled properly to prevent the occurrence of fire and environmental pollution.
Last Update:2024-04-09 20:52:54