181687 - Names and Identifiers
181687 - Physico-chemical Properties
Molecular Formula | C22H16N2O5S
|
Molar Mass | 420.44 |
Solubility | DMSO: ≥ 31 mg/mL |
Storage Condition | -20℃ |
181687 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.378 ml | 11.892 ml | 23.785 ml |
5 mM | 0.476 ml | 2.378 ml | 4.757 ml |
10 mM | 0.238 ml | 1.189 ml | 2.378 ml |
5 mM | 0.048 ml | 0.238 ml | 0.476 ml |
Last Update:2024-01-02 23:10:35
181687 - Reference Information
biological activity | COH29 (RNR Inhibitor COH29) is a potent Inhibitor of rbonucleotide reduction (RNR), has anti-cancer activity. COH29 (RNR Inhibitor COH29) inhibited the activity of recombinant RNR small subunit (RRM1/RRM2) in vitro, and the corresponding IC50 value was 16 μm. |
Target | TargetValue RNR (Cell-free assay) 16 μm |
Target | Value |
RNR
(Cell-free assay)
| 16 μM |
Last Update:2024-04-09 02:00:02