Molecular Formula | C22H16N2O5S |
Molar Mass | 420.44 |
Solubility | DMSO: ≥ 31 mg/mL |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.378 ml | 11.892 ml | 23.785 ml |
5 mM | 0.476 ml | 2.378 ml | 4.757 ml |
10 mM | 0.238 ml | 1.189 ml | 2.378 ml |
5 mM | 0.048 ml | 0.238 ml | 0.476 ml |
biological activity | COH29 (RNR Inhibitor COH29) is a potent Inhibitor of rbonucleotide reduction (RNR), has anti-cancer activity. COH29 (RNR Inhibitor COH29) inhibited the activity of recombinant RNR small subunit (RRM1/RRM2) in vitro, and the corresponding IC50 value was 16 μm. |
Target | TargetValue RNR (Cell-free assay) 16 μm |
Target | Value |
RNR (Cell-free assay) | 16 μM |