182344-14-5

182344-14-5 - Names and Identifiers

Name	(3-Fluoro-4-Hydroxyphenyl)Boronic Acid
Synonyms	AKOS BRN-0728 4-Borono-2-fluorophenol 3-Fluoro-4-hydroxyphenylboronicAcid 3-Fluoro-4-hydroxybezeneboronic acid 3-Fluoro-4-hydroxybenzeneboronicacid 3-Fluoro-4-Hydroxybenzeneboronic Acid 3-Fluoro-4-hydroxybenzeneboronic acid 3-FLUORO-4-HYDROXYBENZENEBORONIC ACID (3-Fluoro-4-Hydroxyphenyl)Boronic Acid (3-FLUORO-4-HYDROXYPHENYL)BORONIC ACID Boronic acid, (3-fluoro-4-hydroxyphenyl)- Boronic acid, (3-fluoro-4-hydroxyphenyl)- (9CI)
CAS	182344-14-5
InChI	InChI=1/C6H6BFO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9-11H

182344-14-5 - Physico-chemical Properties

Molecular Formula	C6H6BFO3
Molar Mass	155.92
Density	1.42±0.1 g/cm3(Predicted)
Melting Point	252-256
Boling Point	331.5±52.0 °C(Predicted)
Flash Point	154.261°C
Water Solubility	Slightly soluble in water.
Vapor Presure	0mmHg at 25°C
pKa	8.01±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.553
MDL	MFCD06659838

182344-14-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

182344-14-5 - Introduction

() Boronic Acid (also known as Boronic Acid) is an organic compound. Its chemical formula is C6H5B(OH)2F, and it has a fluorine atom on a benzene ring and a hydroxyl group attached to the boron atom.

Regarding its nature, (the appearance of) Boronic Acid is a white crystalline solid, soluble in some organic solvents such as chloroform, dimethylformamide, etc., and insoluble in water. It is more stable at high temperatures, but hydrolysis occurs under light or strong alkali conditions.

This compound has several uses in the field of chemical research. It can be used as a reagent and catalyst in organic synthesis. As an aryl boronic acid, it can participate in the construction of aryl boronic acid compounds, for example, by the reduction of phenyl to generate the corresponding aryl boronic alcohol. In addition, it is also used in C- C bond-forming reactions, Suzuki reactions and the like in organic synthesis.

There are many ways to prepare (br) Boronic Acid. A common method is to obtain the product by hydrolysis reaction by reacting p-fluorophenylboronic acid with hydrochloric acid. Another method is the reduction product formed by the reaction of 3-fluoro-4-hydroxyphenylmagnesium bromide with triphenylboron.

When using and handling Boronic Acid, you need to pay attention to some safety information. It should avoid contact with strong bases or oxidizing agents to prevent dangerous reactions. Wear appropriate protective equipment such as goggles and gloves during operation. In addition, should be sealed for storage and avoid exposure to air, moisture and light. Follow local environmental regulations when disposing of waste. For specific safety measures and first aid methods, refer to the product's safety data sheet.

Last Update：2024-04-10 22:29:15