1H-Benzimidazole,2-(difluoromethyl)-(9CI)
2-Difluoromethyl-1H-benzoimidazole
CAS: 705-09-9
Molecular Formula: C8H6F2N2
1H-Benzimidazole,2-(difluoromethyl)-(9CI) - Names and Identifiers
| Name | 2-Difluoromethyl-1H-benzoimidazole |
| Synonyms | 2-(Difluoromethyl) 2-Difluoromethylbenzimidazole 2-(Difluormethyl)-1H-benzimidazol 2-Difluoromethyl-1H-benzoimidazole 2-(Difluoromethyl)-1H-benzimidazole 1H-benzimidazole, 2-(difluoromethyl)- 2-(difluoroMethyl)-1H-1,3-benzodiazole 1H-benzo[d]imidazole, 2-(difluoromethyl)- 1H-Benzimidazole,2-(difluoromethyl)-(9CI) |
| CAS | 705-09-9 |
| InChI | InChI=1/C8H6F2N2/c9-7(10)8-11-5-3-1-2-4-6(5)12-8/h1-4,7H,(H,11,12) |
1H-Benzimidazole,2-(difluoromethyl)-(9CI) - Physico-chemical Properties
| Molecular Formula | C8H6F2N2 |
| Molar Mass | 168.14 |
| Density | 1.366±0.06 g/cm3(Predicted) |
| Melting Point | 155.0 to 159.0 °C |
| Boling Point | 57-62 °C(Press: 5 Torr) |
| Flash Point | 141.1°C |
| Vapor Presure | 0.00114mmHg at 25°C |
| Maximum wavelength(λmax) | 276nm(EtOH)(lit.) |
| pKa | 10.43±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.595 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
1H-Benzimidazole,2-(difluoromethyl)-(9CI) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1H-Benzimidazole,2-(difluoromethyl)-(9CI) - Introduction
It is an organic compound with a chemical formula of C8H5F2N and a relative molecular mass of 161.13. Its nature is as follows:
1. Appearance: It is a white crystalline solid.
2. melting point: about 173-175 degrees Celsius.
3. Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and chloroform, insoluble in water.
About its use:
calcium is an important intermediate compound widely used in the pharmaceutical and pesticide industries. Specific applications include:
1. Drug development: It can be used as an intermediate for the synthesis of antibacterial drugs and antiviral drugs.
2. pesticide manufacturing: used in synthetic pesticides and herbicides and other agricultural chemicals.
3. Chemical synthesis: It can be used for coupling and substitution reactions in organic synthesis.
Preparation Method:
There are many synthesis methods, one of the common synthesis methods is as follows:
By introducing a difluoromethyl group on the benzimidazole ring, a common method is to react with a proper amount of difluoromethylating reagent, such as diiodomethane or diiodomethanesulfonamide, with benzimidazole under suitable reaction conditions to obtain the target product.
Safety Information:
Because it is an organic compound, it poses a potential health and safety risk. Therefore, the following items should be paid attention to in operation and use:
1. Avoid contact with skin, eyes and respiratory tract. In case of contact, immediately flush the affected area with plenty of clean water and seek medical attention.
2. When operating indoors, please ensure adequate ventilation to avoid inhaling its vapors.
3. storage should be kept in a dry, cool, ventilated place, away from fire and flammable materials.
Since the exact safety data depends on the specific experimental conditions and use, please consult and follow the relevant safety technical information and operating instructions before use.
1. Appearance: It is a white crystalline solid.
2. melting point: about 173-175 degrees Celsius.
3. Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and chloroform, insoluble in water.
About its use:
calcium is an important intermediate compound widely used in the pharmaceutical and pesticide industries. Specific applications include:
1. Drug development: It can be used as an intermediate for the synthesis of antibacterial drugs and antiviral drugs.
2. pesticide manufacturing: used in synthetic pesticides and herbicides and other agricultural chemicals.
3. Chemical synthesis: It can be used for coupling and substitution reactions in organic synthesis.
Preparation Method:
There are many synthesis methods, one of the common synthesis methods is as follows:
By introducing a difluoromethyl group on the benzimidazole ring, a common method is to react with a proper amount of difluoromethylating reagent, such as diiodomethane or diiodomethanesulfonamide, with benzimidazole under suitable reaction conditions to obtain the target product.
Safety Information:
Because it is an organic compound, it poses a potential health and safety risk. Therefore, the following items should be paid attention to in operation and use:
1. Avoid contact with skin, eyes and respiratory tract. In case of contact, immediately flush the affected area with plenty of clean water and seek medical attention.
2. When operating indoors, please ensure adequate ventilation to avoid inhaling its vapors.
3. storage should be kept in a dry, cool, ventilated place, away from fire and flammable materials.
Since the exact safety data depends on the specific experimental conditions and use, please consult and follow the relevant safety technical information and operating instructions before use.
Last Update：2024-04-09 21:54:55
Supplier List
Spot supply
Product Name: 2-Difluoromethyl-1H-benzoimidazole Request for quotationCAS: 705-09-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Difluoromethyl-1H-benzoimidazole Request for quotationCAS: 705-09-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: 2-(Difluoromethyl)-1H-benzo[d]imidazole Visit Supplier Webpage Request for quotationCAS: 705-09-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(Difluoromethyl)-1H-benzo[d]imidazole Visit Supplier Webpage Request for quotationCAS: 705-09-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-Difluoromethyl-1H-benzoimidazole Visit Supplier Webpage Request for quotation
CAS: 705-09-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 705-09-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 2-Difluoromethyl-1H-benzoimidazole Request for quotationCAS: 705-09-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Difluoromethyl-1H-benzoimidazole Request for quotationCAS: 705-09-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: 2-(Difluoromethyl)-1H-benzo[d]imidazole Visit Supplier Webpage Request for quotationCAS: 705-09-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(Difluoromethyl)-1H-benzo[d]imidazole Visit Supplier Webpage Request for quotationCAS: 705-09-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-Difluoromethyl-1H-benzoimidazole Visit Supplier Webpage Request for quotation
CAS: 705-09-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 705-09-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
1H-Benzimidazole,2-(difluoromethyl)-(9CI)
Sodium Carbonate Monohydrate
Caprylic triglyceride
Ferrate(3-), tris(oxalato)-, triammonium
Ammonium, tetraethyl-, nitrate
4-[(4,6-Dimethylpyrimidin-2-Yl)Thio]Aniline
(S) 1-BOC-3-hydroxylpyrrolidine
POLY(ETHYLENE SUCCINATE)
丙纶油剂
异辛酯
Sodium Carbonate Monohydrate
Caprylic triglyceride
Ferrate(3-), tris(oxalato)-, triammonium
Ammonium, tetraethyl-, nitrate
4-[(4,6-Dimethylpyrimidin-2-Yl)Thio]Aniline
(S) 1-BOC-3-hydroxylpyrrolidine
POLY(ETHYLENE SUCCINATE)
丙纶油剂
异辛酯