1H-Indole,7-(phenylMethoxy)-

Name	7-benzyloxyindole crystalline
Synonyms	NSC 92526 7-BENZYLOXYINDOLE 7-Benzyloxyindole 7-Benzyloxy-1H-indole 7-(PHENYLMETHOXY)INDOLE 7-(Phenylmethoxy)-1H-indole 1H-Indole,7-(phenylMethoxy)- 7-benzyloxyindolecrystalline 7-benzyloxyindole crystalline
CAS	20289-27-4
InChI	InChI=1/C15H13NO/c1-2-5-12(6-3-1)11-17-14-8-4-7-13-9-10-16-15(13)14/h1-10,16H,11H2

Molecular Formula	C15H13NO
Molar Mass	223.27
Density	1.196±0.06 g/cm3(Predicted)
Melting Point	70-74 °C
Boling Point	411.6±20.0 °C(Predicted)
Flash Point	148.9°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	1.31E-06mmHg at 25°C
Appearance	grayish crystalline powder
Color	Light Red
pKa	16.36±0.30(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.669
MDL	MFCD00037974

Hazard Symbols	Xi - Irritant
Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29339990
Hazard Class	IRRITANT

Overview	7-benzyloxyindole is an organic intermediate, it can be prepared by reacting 7-hydroxyindole with benzyl bromide.
preparation	7-hydroxyindole (300 mg) was dissolved in dimethylformamide (2.0), to the solution were added potassium carbonate (622.6 mg) and benzyl bromide (295 μL) at room temperature, and the mixture was stirred at room temperature overnight. Distilled water and ethyl acetate were added to the reaction mixture for extraction, and the organic layer was washed twice with distilled water, then dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (Hexane: ethyl acetate = 10: 1) to obtain 7-benzyloxyindole (384mg).
Use	for the preparation of pyrazolo quinoline derivatives as adenosine receptor antagonists; For the asymmetric total synthesis of azide Amides; for the preparation of HCV inhibitors; For the preparation of substituted 3-cyanoindoles and 3-(4-pyridyl) indoles as inhibitors of creatine monophosphate dehydrogenase in peripheral mononuclear blood cells (PMBC) has anti-proliferative activity; For the preparation of indolylmethylhydantoin and thiohydantoin derivatives for the treatment of apoptosis; For the preparation of ED-110, regioisomeric analogs

of the Human topoisomerase indolizino-azepoene poison

Last Update：2024-04-09 21:04:16

Multiple Specifications

Product Name: 7-Benzyloxyindole Visit Supplier Webpage Request for quotation
CAS: 20289-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Multiple Specifications

Product Name: 7-Benzyloxyindole Visit Supplier Webpage Request for quotation
CAS: 20289-27-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

1H-Indole,7-(phenylMethoxy)-

1H-Indole,7-(phenylMethoxy)- Request for Quotation