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7-BENZYLOXYINDOLE

7-benzyloxyindole crystalline

CAS: 20289-27-4

Molecular Formula: C15H13NO

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7-BENZYLOXYINDOLE - Names and Identifiers

Name 7-benzyloxyindole crystalline
Synonyms NSC 92526
7-BENZYLOXYINDOLE
7-Benzyloxyindole
7-Benzyloxy-1H-indole
7-(PHENYLMETHOXY)INDOLE
7-(Phenylmethoxy)-1H-indole
1H-Indole,7-(phenylMethoxy)-
7-benzyloxyindolecrystalline
7-benzyloxyindole crystalline
CAS 20289-27-4
InChI InChI=1/C15H13NO/c1-2-5-12(6-3-1)11-17-14-8-4-7-13-9-10-16-15(13)14/h1-10,16H,11H2

7-BENZYLOXYINDOLE - Physico-chemical Properties

Molecular FormulaC15H13NO
Molar Mass223.27
Density1.196±0.06 g/cm3(Predicted)
Melting Point70-74 °C
Boling Point411.6±20.0 °C(Predicted)
Flash Point148.9°C
Solubility Chloroform (Slightly), Methanol (Slightly)
Vapor Presure1.31E-06mmHg at 25°C
Appearancegrayish crystalline powder
ColorLight Red
pKa16.36±0.30(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
Refractive Index1.669
MDLMFCD00037974

7-BENZYLOXYINDOLE - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Safety Description24/25 - Avoid contact with skin and eyes.
WGK Germany3
HS Code29339990
Hazard ClassIRRITANT

7-BENZYLOXYINDOLE - Reference Information

Overview 7-benzyloxyindole is an organic intermediate, it can be prepared by reacting 7-hydroxyindole with benzyl bromide.
preparation 7-hydroxyindole (300 mg) was dissolved in dimethylformamide (2.0), to the solution were added potassium carbonate (622.6 mg) and benzyl bromide (295 μL) at room temperature, and the mixture was stirred at room temperature overnight. Distilled water and ethyl acetate were added to the reaction mixture for extraction, and the organic layer was washed twice with distilled water, then dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (Hexane: ethyl acetate = 10: 1) to obtain 7-benzyloxyindole (384mg).
Use for the preparation of pyrazolo quinoline derivatives as adenosine receptor antagonists; For the asymmetric total synthesis of azide Amides; for the preparation of HCV inhibitors; For the preparation of substituted 3-cyanoindoles and 3-(4-pyridyl) indoles as inhibitors of creatine monophosphate dehydrogenase in peripheral mononuclear blood cells (PMBC) has anti-proliferative activity; For the preparation of indolylmethylhydantoin and thiohydantoin derivatives for the treatment of apoptosis; For the preparation of ED-110, regioisomeric analogs
of the Human topoisomerase indolizino-azepoene poison
Last Update:2024-04-09 21:04:16
7-BENZYLOXYINDOLE
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QQ: 2881950922 Click to send a QQ message
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: 7-Benzyloxyindole Visit Supplier Webpage Request for quotation
CAS: 20289-27-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Product Name: 7-Benzyloxyindole Visit Supplier Webpage Request for quotation
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