1H-Indole-5-acetonitrile
1H-Indole-5-acetonitrile
CAS: 23690-49-5
Molecular Formula: C10H8N2
1H-Indole-5-acetonitrile - Names and Identifiers
1H-Indole-5-acetonitrile - Physico-chemical Properties
| Molecular Formula | C10H8N2 |
| Molar Mass | 156.18 |
| Density | 1.219±0.06 g/cm3(Predicted) |
| Melting Point | 58 °C |
| Boling Point | 374.1±17.0 °C(Predicted) |
| pKa | 16.61±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
1H-Indole-5-acetonitrile - Introduction
1H-Indole-5-acetonitrile is an organic compound with the chemical formula C10H8N2. It is a colorless to light yellow crystal with a bitter taste. It has physical properties such as a melting point as high as 85-88°C and a boiling point of 274-276°C.
1H-Indole-5-acetonitrile is a substrate commonly used in drug synthesis and organic synthesis. It can be used as an intermediate of indole compounds for the preparation of natural products, drugs and pesticides and other organic synthesis reactions. In addition, it is also used in the research field for the synthesis of indole derivatives and the development of new drugs.
The method of preparing 1H-Indole-5-acetonitrile can be achieved by introducing a cyano group on the nitrogen atom of indole. In the reaction, indole is reacted with cyanide, and cyanation is carried out under basic conditions to produce 1H-Indole-5-acetonitrile.
Regarding safety information, 1H-Indole-5-acetonitrile is stable under general conditions, but may react dangerously at high temperatures, high pressures or when in contact with strong oxidants. It is an organic compound with certain toxicity and may cause irritation to the skin, eyes and respiratory tract. When using, care should be taken to avoid skin contact and inhalation. If you accidentally come into contact with skin or eyes, rinse with plenty of water and seek medical help. At the same time, pay attention to fire and explosion prevention during storage and handling, and store it in a sealed container. When using, you should pay attention to personal protective measures, such as wearing gloves, goggles and laboratory coats.
1H-Indole-5-acetonitrile is a substrate commonly used in drug synthesis and organic synthesis. It can be used as an intermediate of indole compounds for the preparation of natural products, drugs and pesticides and other organic synthesis reactions. In addition, it is also used in the research field for the synthesis of indole derivatives and the development of new drugs.
The method of preparing 1H-Indole-5-acetonitrile can be achieved by introducing a cyano group on the nitrogen atom of indole. In the reaction, indole is reacted with cyanide, and cyanation is carried out under basic conditions to produce 1H-Indole-5-acetonitrile.
Regarding safety information, 1H-Indole-5-acetonitrile is stable under general conditions, but may react dangerously at high temperatures, high pressures or when in contact with strong oxidants. It is an organic compound with certain toxicity and may cause irritation to the skin, eyes and respiratory tract. When using, care should be taken to avoid skin contact and inhalation. If you accidentally come into contact with skin or eyes, rinse with plenty of water and seek medical help. At the same time, pay attention to fire and explosion prevention during storage and handling, and store it in a sealed container. When using, you should pay attention to personal protective measures, such as wearing gloves, goggles and laboratory coats.
Last Update：2024-04-09 21:11:58
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Product Name: 1H-Indole,5-acetonitrile Visit Supplier Webpage Request for quotation
CAS: 23690-49-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 23690-49-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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