2,2,2-Trifluoro-1-methyl-ethylamine

2,2,2-Trifluoro-1-methyl-ethylamine - Names and Identifiers

Name	1,1,1-Trifluoro-isopropylamine
Synonyms	ATF 1,1,1-trifluoropropan-2-amine 1,1,1-Trifluoro-2-propanaMine 1,1,1-Trifluoroprop-2-ylaMine 1,1,1-Trifluoro-isopropylamine 2-Amino-1,1,1-trifluoropropane 1,1,1-Trifluoro-2-aMinopropane 1,1,1-TRIFLUORO-ISOPROPYLAMINE 2,2,2-Trifluoro-1-methyl-ethylamine (2,2,2-Trifluoro-1-methylethyl)amine
CAS	421-49-8

2,2,2-Trifluoro-1-methyl-ethylamine - Physico-chemical Properties

Molecular Formula	C3H6F3N
Molar Mass	113.08
Density	1.148±0.06 g/cm3(Predicted)
Melting Point	0°C
Boling Point	0°C
Flash Point	0°C
pKa	5.82±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

2,2,2-Trifluoro-1-methyl-ethylamine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	2734
Hazard Class	IRRITANT

2,2,2-Trifluoro-1-methyl-ethylamine - Introduction

1,1,1-Trifluoro-isopropylamine, also known as 1,1, 1-trifluoro-2-propylamine, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless transparent liquid
-Molecular formula: C3H6F3N
-Molecular weight: 113.08g/mol
-Melting point:-145°C
-Boiling Point: 38°C
-Density: 1.09 g/mL

Use:
- 1,1,1-Trifluoro-isopropylamine is commonly used as a medium or reagent in organic synthesis. It is an important C- F bond activating reagent and has applications in the pharmaceutical and pesticide industries.
-It can be used in the reaction of fluorinated hydrocarbons and ammonia to prepare compounds containing trifluoromethyl groups.
-It can also be used for the synthesis of catalysts, the preparation of fungicides and the synthesis of organometallic compounds.

Preparation Method:
-A commonly used preparation method is to react trifluoromethyl bromide (CF3Br) with ammonia (NH3) under alkaline conditions to generate 1,1,1-Trifluoro-isopropylamine.

Safety Information:
- 1,1,1-Trifluoro-isopropylamine is an organic compound, you need to pay attention to its safety when used.
-It is irritating and corrosive, and may cause burns after contact with skin and eyes. Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing when operating.
-During storage and use, avoid contact with oxidants and combustibles, and avoid inhaling their vapors.
-need to operate in a well-ventilated place, and comply with the relevant safety procedures.

Last Update：2024-04-09 19:05:50

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