2-Amino-1,1,1-trifluoropropane - Names and Identifiers
Name | 1,1,1-Trifluoro-isopropylamine
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Synonyms | ATF 1,1,1-trifluoropropan-2-amine 1,1,1-Trifluoro-2-propanaMine 1,1,1-Trifluoroprop-2-ylaMine 1,1,1-Trifluoro-isopropylamine 2-Amino-1,1,1-trifluoropropane 1,1,1-Trifluoro-2-aMinopropane 1,1,1-TRIFLUORO-ISOPROPYLAMINE 2,2,2-Trifluoro-1-methyl-ethylamine (2,2,2-Trifluoro-1-methylethyl)amine
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CAS | 421-49-8
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2-Amino-1,1,1-trifluoropropane - Physico-chemical Properties
Molecular Formula | C3H6F3N
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Molar Mass | 113.08 |
Density | 1.148±0.06 g/cm3(Predicted) |
Melting Point | 0°C |
Boling Point | 0°C |
Flash Point | 0°C |
pKa | 5.82±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
2-Amino-1,1,1-trifluoropropane - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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UN IDs | 2734 |
Hazard Class | IRRITANT |
2-Amino-1,1,1-trifluoropropane - Introduction
1,1,1-Trifluoro-isopropylamine, also known as 1,1, 1-trifluoro-2-propylamine, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless transparent liquid
-Molecular formula: C3H6F3N
-Molecular weight: 113.08g/mol
-Melting point:-145°C
-Boiling Point: 38°C
-Density: 1.09 g/mL
Use:
- 1,1,1-Trifluoro-isopropylamine is commonly used as a medium or reagent in organic synthesis. It is an important C- F bond activating reagent and has applications in the pharmaceutical and pesticide industries.
-It can be used in the reaction of fluorinated hydrocarbons and ammonia to prepare compounds containing trifluoromethyl groups.
-It can also be used for the synthesis of catalysts, the preparation of fungicides and the synthesis of organometallic compounds.
Preparation Method:
-A commonly used preparation method is to react trifluoromethyl bromide (CF3Br) with ammonia (NH3) under alkaline conditions to generate 1,1,1-Trifluoro-isopropylamine.
Safety Information:
- 1,1,1-Trifluoro-isopropylamine is an organic compound, you need to pay attention to its safety when used.
-It is irritating and corrosive, and may cause burns after contact with skin and eyes. Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing when operating.
-During storage and use, avoid contact with oxidants and combustibles, and avoid inhaling their vapors.
-need to operate in a well-ventilated place, and comply with the relevant safety procedures.
Last Update:2024-04-09 19:05:50