2,3,6-TRIFLUOROACETOPHENONE - Names and Identifiers
Name | 2,3,6-trifluoroacetophenone
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Synonyms | 2,3,6-TRIFLUOROACETOPHENONE 2,3,6-trifluoroacetophenone 2',3',6'-TRIFLUOROACETOPHENONE 2',3',6'-trifluoroacetophenone 1-(2,3,6-Trifluorophenyl)ethanone 1-(2,3,6-trifluorophenyl)ethanone Ethanone, 1-(2,3,6-trifluorophenyl)- 1-(2,3,6-trifluorophenyl)ethan-1-one 1-(2,3,6-Trifluorophenyl)ethan-1-one, 1-Oxo-1-(2,3,6-trifluorophenyl)ethane
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CAS | 208173-22-2
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InChI | InChI=1/C8H5F3O/c1-4(12)7-5(9)2-3-6(10)8(7)11/h2-3H,1H3 |
2,3,6-TRIFLUOROACETOPHENONE - Physico-chemical Properties
Molecular Formula | C8H5F3O
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Molar Mass | 174.12 |
Density | 1.303±0.06 g/cm3(Predicted) |
Boling Point | 187.2±35.0 °C(Predicted) |
Flash Point | 65°C |
Vapor Presure | 0.637mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.467 |
MDL | MFCD00070809 |
2,3,6-TRIFLUOROACETOPHENONE - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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UN IDs | 1224 |
Hazard Note | Irritant/Flammable |
Hazard Class | IRRITANT |
Packing Group | III |
2,3,6-TRIFLUOROACETOPHENONE - Introduction
2,3,6-trifluoroacetophenone, also known as trifluoroacetophenone, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2,3,6-trifluoroacetophenone is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, ether and chloroform, and insoluble in water.
-Melting point: About -20 ° C.
-Boiling point: about 105 ° C.
Use:
- 2,3,6-trifluoroacetophenone is widely used in the field of organic synthesis and is commonly used as a fluorination reagent for fluorine compounds.
-It is also used as a key raw material in the field of dyes, organic synthesis intermediates and pharmaceuticals.
Method:
2,3,6-trifluoroacetophenone can be prepared by the following methods:
-Fluorination reaction of aromatic compounds: The corresponding acetophenone is reacted with fluorine gas under appropriate catalyst and conditions, and the fluorination reaction is carried out in an appropriate solvent.
-Reaction of fluorination reagent: The fluorination reagent (such as boron trifluoride, lithium fluoride, etc.) is reacted with the corresponding aromatic substance, and then through appropriate steps to obtain 2,3,6-trifluoroacetophenone.
Safety Information:
- 2,3,6-trifluoroacetophenone is a chemical that should be used with caution.
-During use, appropriate protective measures need to be taken, such as wearing chemical protective gloves and goggles to ensure good ventilation conditions.
-Avoid inhalation, ingestion or contact with skin and eyes to avoid irritation and injury.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.
Last Update:2024-04-09 02:00:44