208173-22-2

208173-22-2 - Names and Identifiers

Name	2,3,6-trifluoroacetophenone
Synonyms	2,3,6-TRIFLUOROACETOPHENONE 2,3,6-trifluoroacetophenone 2',3',6'-TRIFLUOROACETOPHENONE 2',3',6'-trifluoroacetophenone 1-(2,3,6-Trifluorophenyl)ethanone 1-(2,3,6-trifluorophenyl)ethanone Ethanone, 1-(2,3,6-trifluorophenyl)- 1-(2,3,6-trifluorophenyl)ethan-1-one 1-(2,3,6-Trifluorophenyl)ethan-1-one, 1-Oxo-1-(2,3,6-trifluorophenyl)ethane
CAS	208173-22-2
InChI	InChI=1/C8H5F3O/c1-4(12)7-5(9)2-3-6(10)8(7)11/h2-3H,1H3

208173-22-2 - Physico-chemical Properties

Molecular Formula	C8H5F3O
Molar Mass	174.12
Density	1.303±0.06 g/cm3(Predicted)
Boling Point	187.2±35.0 °C(Predicted)
Flash Point	65°C
Vapor Presure	0.637mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.467
MDL	MFCD00070809

208173-22-2 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	1224
Hazard Note	Irritant/Flammable
Hazard Class	IRRITANT
Packing Group	III

208173-22-2 - Introduction

2,3,6-trifluoroacetophenone, also known as trifluoroacetophenone, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 2,3,6-trifluoroacetophenone is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, ether and chloroform, and insoluble in water.
-Melting point: About -20 ° C.
-Boiling point: about 105 ° C.

Use:
- 2,3,6-trifluoroacetophenone is widely used in the field of organic synthesis and is commonly used as a fluorination reagent for fluorine compounds.
-It is also used as a key raw material in the field of dyes, organic synthesis intermediates and pharmaceuticals.

Method:
2,3,6-trifluoroacetophenone can be prepared by the following methods:
-Fluorination reaction of aromatic compounds: The corresponding acetophenone is reacted with fluorine gas under appropriate catalyst and conditions, and the fluorination reaction is carried out in an appropriate solvent.
-Reaction of fluorination reagent: The fluorination reagent (such as boron trifluoride, lithium fluoride, etc.) is reacted with the corresponding aromatic substance, and then through appropriate steps to obtain 2,3,6-trifluoroacetophenone.

Safety Information:
- 2,3,6-trifluoroacetophenone is a chemical that should be used with caution.
-During use, appropriate protective measures need to be taken, such as wearing chemical protective gloves and goggles to ensure good ventilation conditions.
-Avoid inhalation, ingestion or contact with skin and eyes to avoid irritation and injury.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.

Last Update：2024-04-09 02:00:44