2,6,6-trimethylcyclohepta-2,4-dien-1-one

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Names and Identifiers

Name	2,6,6-trimethylcyclohepta-2,4-dien-1-one
Synonyms	Eucarvon 2,4-Cycloheptadien-1-one,2 2,6,6-TRIMETHYL-CYCLOHEPTA-2,4-DIENONE 2,6,6-TRIMETHYL-2,4-CYCLOHEPTADIEN-1-ONE 2,6,6-trimethylcyclohepta-2,4-dien-1-one 2,4-Cycloheptadien-1-one, 2,6,6-trimethyl-
CAS	503-93-5
InChI	InChI=1/C10H14O/c1-8-5-4-6-10(2,3)7-9(8)11/h4-6H,7H2,1-3H3

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Physico-chemical Properties

Molecular Formula	C10H14O
Molar Mass	150.22
Density	0,95 g/cm3
Melting Point	87-89 °C
Boling Point	82°C 10mm
Flash Point	90.3°C
Solubility	Soluble in ethanol and acetone.
Vapor Presure	0.08mmHg at 25°C
Appearance	Liquid
Storage Condition	2-8℃
Refractive Index	1.5070-1.5100
MDL	MFCD00182537
Use	Summary Pueraria lobata ketone (Eucarvone) is an extract, widely exists in Artemisia argyi, Asarum, Mosla, substituted flowers, black pepper, duheng, Angelica, frankincense and horseshoe and other traditional Chinese medicine.

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Upstream Downstream Industry

Raw Materials	2,4-Cycloheptadien-1-one, 3,6,6-trimethyl- 2-Cyclohexen-1-one, 5-(1-bromo-1-methylethyl)-2-methyl-, (S)- (9CI) (S)-3-Methyl-6β-isopropenyl-2-cyclohexene-1-one 3-methyl-6-(1-methylethylidene)cyclohex-2-en-1-one 3-CARENE Thymol (+)-Dipentene
Downstream Products	Carvacrol

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Reference

Reference

1. Wu, Mei, et al. "Fumigant Toxicity and Oviposition Deterrent Activity of Volatile Constituents from Asari Radix et Rhizoma against Phthorimaea operculella (Lepidoptera: Gelechiidae)." Journal of Insect Science 20.6 (2020): 32.https://doi.org/10.1093/jisesa

2,6,6-trimethylcyclohepta-2,4-dien-1-one - Introduction

2,6,6-trimethylcyclohepta-2,4-dien-1-one, also known as bridge-cycloheptanone, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow liquid.
-Molar mass: 154.26g/mol.
-Density: 0.872g/cm³.
-Melting point:-8 ° C.
-Boiling point: 168-170 ° C.
-Solubility: Soluble in general organic solvents.

Use:
-bridged cycloheptanone is commonly used as an intermediate in organic synthesis.
-In the field of medicine, it can be used to synthesize antibacterial agents, antiviral compounds, etc.
-In addition, bridged cycloheptanone can also be used for the preparation of coatings and hybrid materials.

Preparation Method:
-The synthesis of bridged cycloheptanone can be obtained by acid-catalyzed protonation of cycloheptadiene and methylcyclohexane. During the reaction, the diene reacts with the methylating agent to form 1-methyl -2-methyl cyclohexene, followed by protonation to obtain the desired bridged cycloheptanone.

Safety Information:
-bridge cycloheptanone can cause eye and skin irritation, so pay attention to avoid contact with skin and eyes when using.
-If inhaled, the vapors of the bridge cycloheptanone may cause symptoms such as dizziness, drowsiness and loss of consciousness. Therefore, it is necessary to provide good ventilation during handling and storage.
-When the bridge cycloheptanone leaks, appropriate cleaning and treatment measures should be taken to avoid further danger.

Last Update：2024-04-09 20:52:54