2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine

2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine - Names and Identifiers

Name	3-Cyano-2,6-dihydroxy-5-fluoropyridine
Synonyms	2,6-Dihydroxy-5-fluoronicotinonitrile 5-FLUORO-2,6-DIHYDROXYNICOTINONITRILE 6-Dihydroxy-5-fluoro-3-cyano-pyridine 3-CYANO-2,6-DIHYDROXY-5-FLUOROPYRIDINE 3-Cyano-2,6-dihydroxy-5-fluoropyridine 2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine 2,6-DIHYDROXY-3-CYANO-5-FLUOROPYRIDINE 2.6-dihydroxy-5-fluoro-3-cyanopyridine 2,6-Dihydroxy-5-fluoro-3-cyano-pyridine 2,6-DIHYDROXY-5-FLUORO-3-CYANO-PYRIDINE 5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril 5-fluoro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carbonitrile 5-Fluoro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS	113237-18-6
InChI	InChI=1/C6H3FN2O2/c7-4-1-3(2-8)5(10)9-6(4)11/h1H,(H2,9,10,11)

2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine - Physico-chemical Properties

Molecular Formula	C6H3FN2O2
Molar Mass	154.1
Density	1.58±0.1 g/cm3(Predicted)
Melting Point	235-245 °C
Boling Point	217.5±40.0 °C(Predicted)
Flash Point	85.4°C
Vapor Presure	0.0283mmHg at 25°C
pKa	1.43±0.58(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.578

2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine - Introduction

2,6-Dihydroxy-5-fluoro-3-cyanopyridine is an organic compound with the chemical formula C7H4FNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2,6-Dihydroxy-5-fluoro-3-cyanopyridine is a white crystalline solid.
-Melting point: Its melting point is about 160-165 degrees Celsius.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents such as ethanol, formic acid and dichloromethane.
-Chemical properties: It is a compound with aromatic properties. It also contains fluorine and cyano groups and has certain chemical reactivity.

Use:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine can be used as a pesticide intermediate for the synthesis of enantiomerically pure pesticide active ingredients.
-It can also be used to prepare pharmaceutical intermediates, such as antibiotics, antiviral drugs and anti-cancer drugs.

Preparation Method:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine can be synthesized by a variety of synthetic methods. A common preparation method is to react 2,6-dihydroxy-3-cyanopyridine with a fluorine compound to produce the target product.
-During the preparation process, attention should be paid to the safety of operation and the use of appropriate experimental equipment.

Safety Information:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine is relatively stable under general conditions, but it has strong sensitivity to high temperature, fire source and oxidant, and needs to be properly preserved.
-Wear appropriate personal protective equipment such as lab coat, gloves and goggles during operation and synthesis.
-When handling this compound, avoid direct contact with the skin and inhalation of its dust. After the operation is completed, clean the hands and work area in time.
-If the compound is inhaled or ingested, seek medical attention and provide prompt in-room treatment to your doctor.

Last Update：2024-04-09 19:05:46