5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril - Names and Identifiers
Name | 3-Cyano-2,6-dihydroxy-5-fluoropyridine
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Synonyms | 2,6-Dihydroxy-5-fluoronicotinonitrile 5-FLUORO-2,6-DIHYDROXYNICOTINONITRILE 6-Dihydroxy-5-fluoro-3-cyano-pyridine 3-CYANO-2,6-DIHYDROXY-5-FLUOROPYRIDINE 3-Cyano-2,6-dihydroxy-5-fluoropyridine 2,6-Dihydroxy-5-Fluoro-3-Cyanopyridine 2,6-DIHYDROXY-3-CYANO-5-FLUOROPYRIDINE 2.6-dihydroxy-5-fluoro-3-cyanopyridine 2,6-Dihydroxy-5-fluoro-3-cyano-pyridine 2,6-DIHYDROXY-5-FLUORO-3-CYANO-PYRIDINE 5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril 5-fluoro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carbonitrile 5-Fluoro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carbonitrile
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CAS | 113237-18-6
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InChI | InChI=1/C6H3FN2O2/c7-4-1-3(2-8)5(10)9-6(4)11/h1H,(H2,9,10,11) |
5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril - Physico-chemical Properties
Molecular Formula | C6H3FN2O2
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Molar Mass | 154.1 |
Density | 1.58±0.1 g/cm3(Predicted) |
Melting Point | 235-245 °C |
Boling Point | 217.5±40.0 °C(Predicted) |
Flash Point | 85.4°C |
Vapor Presure | 0.0283mmHg at 25°C |
pKa | 1.43±0.58(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.578 |
5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
5-fluoro-1,2-dihydro-6-hydroxy-2-oxo-3-pyridinecarbonitril - Introduction
2,6-Dihydroxy-5-fluoro-3-cyanopyridine is an organic compound with the chemical formula C7H4FNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,6-Dihydroxy-5-fluoro-3-cyanopyridine is a white crystalline solid.
-Melting point: Its melting point is about 160-165 degrees Celsius.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents such as ethanol, formic acid and dichloromethane.
-Chemical properties: It is a compound with aromatic properties. It also contains fluorine and cyano groups and has certain chemical reactivity.
Use:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine can be used as a pesticide intermediate for the synthesis of enantiomerically pure pesticide active ingredients.
-It can also be used to prepare pharmaceutical intermediates, such as antibiotics, antiviral drugs and anti-cancer drugs.
Preparation Method:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine can be synthesized by a variety of synthetic methods. A common preparation method is to react 2,6-dihydroxy-3-cyanopyridine with a fluorine compound to produce the target product.
-During the preparation process, attention should be paid to the safety of operation and the use of appropriate experimental equipment.
Safety Information:
-2,6-dihydroxy-5-fluoro-3-cyanopyridine is relatively stable under general conditions, but it has strong sensitivity to high temperature, fire source and oxidant, and needs to be properly preserved.
-Wear appropriate personal protective equipment such as lab coat, gloves and goggles during operation and synthesis.
-When handling this compound, avoid direct contact with the skin and inhalation of its dust. After the operation is completed, clean the hands and work area in time.
-If the compound is inhaled or ingested, seek medical attention and provide prompt in-room treatment to your doctor.
Last Update:2024-04-09 19:05:46