2,6-二氯吡啶-3-羰酰氯
2,6-二氯吡啶-3-羰酰氯
CAS: 58584-83-1
Molecular Formula: C6H2Cl3NO
2,6-二氯吡啶-3-羰酰氯 - Names and Identifiers
2,6-二氯吡啶-3-羰酰氯 - Physico-chemical Properties
| Molecular Formula | C6H2Cl3NO |
| Molar Mass | 210.45 |
| Density | 1.582±0.06 g/cm3(Predicted) |
| Melting Point | 24-30 °C |
| Boling Point | 72-74 °C(Press: 0.01 Torr) |
| Flash Point | 110°C |
| Solubility | Dichloromethane, Ethyl Acetate, Toluene |
| pKa | -5.16±0.10(Predicted) |
2,6-二氯吡啶-3-羰酰氯 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R22 - Harmful if swallowed R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3261 8/PG 2 |
| WGK Germany | 3 |
2,6-二氯吡啶-3-羰酰氯 - Introduction
2,6-dichloropyridine-3-carbonyl chloride, also known as 2,6-dichloropyridine-3-carbonyl chloride, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless to light yellow liquid;
-Density: about 1.57 g/mL;
-Boiling point: about 258-259°C;
-Solubility: Soluble in non-polar organic solvents such as ether, dichloromethane and benzene.
Use:
-2,6-dichloropyridine-3-carbonyl chloride is often used as an important reagent in organic synthesis;
-it can be used for the synthesis of pyridine substances, imidazole compounds and other nitrogen-containing compounds;
-For example, it can be used for sulfonation reaction, amidation reaction and chlorination reaction.
Preparation Method:
-2,6-dichloropyridine-3-carbonyl chloride is usually prepared by the following steps:
(1) reacting 2,6-dichloropyridine with thionyl chloride in an appropriate solvent;
(2) add the solution of thionyl chloride at low temperature, and slowly add nitric acid and diethyl nitrite dropwise;
(3) After the reaction, the product is purified by crystallization and subsequent purification steps.
Safety Information:
-2,6-dichloropyridine-3-carbonyl chloride is corrosive and may cause serious eye and skin damage after contact;
-Wear appropriate protective gloves to protect eyes and skin during operation;
-If inhaled or taken by mistake, seek medical attention immediately;
-Avoid contact with strong oxidants and acids during operation;
-Please observe the relevant safety procedures and store and handle the compound correctly.
Nature:
-Appearance: colorless to light yellow liquid;
-Density: about 1.57 g/mL;
-Boiling point: about 258-259°C;
-Solubility: Soluble in non-polar organic solvents such as ether, dichloromethane and benzene.
Use:
-2,6-dichloropyridine-3-carbonyl chloride is often used as an important reagent in organic synthesis;
-it can be used for the synthesis of pyridine substances, imidazole compounds and other nitrogen-containing compounds;
-For example, it can be used for sulfonation reaction, amidation reaction and chlorination reaction.
Preparation Method:
-2,6-dichloropyridine-3-carbonyl chloride is usually prepared by the following steps:
(1) reacting 2,6-dichloropyridine with thionyl chloride in an appropriate solvent;
(2) add the solution of thionyl chloride at low temperature, and slowly add nitric acid and diethyl nitrite dropwise;
(3) After the reaction, the product is purified by crystallization and subsequent purification steps.
Safety Information:
-2,6-dichloropyridine-3-carbonyl chloride is corrosive and may cause serious eye and skin damage after contact;
-Wear appropriate protective gloves to protect eyes and skin during operation;
-If inhaled or taken by mistake, seek medical attention immediately;
-Avoid contact with strong oxidants and acids during operation;
-Please observe the relevant safety procedures and store and handle the compound correctly.
Last Update：2024-04-09 02:00:57
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Product Name: 2,6-Dichloronicotinoyl chloride Visit Supplier Webpage Request for quotationCAS: 58584-83-1
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Spot supply
Product Name: 2,6-Dichloronicotinoyl chloride Visit Supplier Webpage Request for quotationCAS: 58584-83-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2,6-Dichloronicotinoyl chloride Visit Supplier Webpage Request for quotationCAS: 58584-83-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
2,6-二氯吡啶-3-羰酰氯
Reactive Red RB
AMINO-(2-TRIFLUOROMETHOXY-PHENYL)-ACETIC ACID
4-碘-3,5-二甲基苯甲酰胺
4-氟苯基炔丙基醚
补骨脂色烯查尔酮
(2-氯乙基)(甲基)氨基甲酸叔丁酯
Tadanafil EP or USP impurity C
N,N-二甲基-3-甲胺甲基苯甲酰胺盐酸盐
Acepyrene
Reactive Red RB
AMINO-(2-TRIFLUOROMETHOXY-PHENYL)-ACETIC ACID
4-碘-3,5-二甲基苯甲酰胺
4-氟苯基炔丙基醚
补骨脂色烯查尔酮
(2-氯乙基)(甲基)氨基甲酸叔丁酯
Tadanafil EP or USP impurity C
N,N-二甲基-3-甲胺甲基苯甲酰胺盐酸盐
Acepyrene