2-(2-Pyridinyl)thiophene
2-(2-thienyl)pyridine
CAS: 3319-99-1
Molecular Formula: C9H7NS
2-(2-Pyridinyl)thiophene - Names and Identifiers
| Name | 2-(2-thienyl)pyridine |
| Synonyms | AKOS BAR-1355 BUTTPARK 37 4-10 2-THIEN-2-YLPYRIDINE 2-(2-thienyl)pyridine 2-(2-THIENYL)PYRIDINE 2-(2-Pyridyl)thiophene Pyridine, 2-(2-thienyl)- 2-(2-Pyridinyl)thiophene 2-(thiophen-2-yl)pyridine |
| CAS | 3319-99-1 |
| EINECS | 222-022-1 |
| InChI | InChI=1/C9H7NS/c1-2-6-10-8(4-1)9-5-3-7-11-9/h1-7H |
2-(2-Pyridinyl)thiophene - Physico-chemical Properties
| Molecular Formula | C9H7NS |
| Molar Mass | 161.22 |
| Density | 1.173±0.06 g/cm3(Predicted) |
| Melting Point | 61-63°C |
| Boling Point | 140°C/16mmHg(lit.) |
| Flash Point | 115°C |
| Vapor Presure | 0.013mmHg at 25°C |
| BRN | 508454 |
| pKa | 4.51±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.604 |
| MDL | MFCD00044441 |
2-(2-Pyridinyl)thiophene - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29349990 |
| Hazard Class | IRRITANT |
2-(2-Pyridinyl)thiophene - Introduction
2-(2-thienyl) pyriridine (2-(2-thienyl) pyriridine) is an organic compound with the chemical formula C9H7NS. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-(2-thienyl)pyridine is a colorless to yellow crystal or powdery substance.
-Melting point: about 65-70 ℃.
-Solubility: The compound is soluble in common organic solvents such as dimethyl sulfoxide, methanol, chloroform and ethanol.
Use:
- 2-(2-thienyl)pyridine is widely used as an organic semiconductor and fluorescent dye in devices such as organic light-emitting diodes (OLED) and organic solar cells.
-The compound is also used as a synthetic intermediate for some fluorescent probes, biomarkers and anti-tumor drugs.
Method:
- 2-(2-thienyl)pyridine can be obtained by the reaction of 2-hydrazonopyridine and 2-thiophenyl borate. First, 2-hydrazonoylpyridine and a boronic acid ester are reacted under basic conditions to form a boronic acid hydrazone. Then, a solution of boronic acid hydrazone was obtained by funnel separation. Finally, 2-(2-thienyl)pyridine is generated by heating the boronic acid hydrazone solution in the presence of thiophenol.
Safety Information:
- 2-(2-thienyl)pyridine has no obvious toxicity to human body under normal use conditions.
-However, the compound may have irritating effects on the eyes, skin and respiratory tract. Pay attention to protective measures when exposed.
-Avoid inhaling its dust or vapor, and avoid contact with strong oxidants and strong acids.
-When using or handling the substance, wear suitable personal protective equipment, such as gloves and safety glasses, and ensure that the operation is carried out in a well-ventilated place. Always read and understand the relevant safety data sheets before any processing.
Nature:
-Appearance: 2-(2-thienyl)pyridine is a colorless to yellow crystal or powdery substance.
-Melting point: about 65-70 ℃.
-Solubility: The compound is soluble in common organic solvents such as dimethyl sulfoxide, methanol, chloroform and ethanol.
Use:
- 2-(2-thienyl)pyridine is widely used as an organic semiconductor and fluorescent dye in devices such as organic light-emitting diodes (OLED) and organic solar cells.
-The compound is also used as a synthetic intermediate for some fluorescent probes, biomarkers and anti-tumor drugs.
Method:
- 2-(2-thienyl)pyridine can be obtained by the reaction of 2-hydrazonopyridine and 2-thiophenyl borate. First, 2-hydrazonoylpyridine and a boronic acid ester are reacted under basic conditions to form a boronic acid hydrazone. Then, a solution of boronic acid hydrazone was obtained by funnel separation. Finally, 2-(2-thienyl)pyridine is generated by heating the boronic acid hydrazone solution in the presence of thiophenol.
Safety Information:
- 2-(2-thienyl)pyridine has no obvious toxicity to human body under normal use conditions.
-However, the compound may have irritating effects on the eyes, skin and respiratory tract. Pay attention to protective measures when exposed.
-Avoid inhaling its dust or vapor, and avoid contact with strong oxidants and strong acids.
-When using or handling the substance, wear suitable personal protective equipment, such as gloves and safety glasses, and ensure that the operation is carried out in a well-ventilated place. Always read and understand the relevant safety data sheets before any processing.
Last Update：2024-04-09 21:01:54
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