2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one

2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one - Names and Identifiers

Name	2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone
Synonyms	2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone Ethanone, 2-(4-broMophenyl)-1-(2,4-dihydroxyphenyl)- 2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one
CAS	92152-60-8
InChI	InChI=1/C14H11BrO3/c15-10-3-1-9(2-4-10)7-13(17)12-6-5-11(16)8-14(12)18/h1-6,8,16,18H,7H2

2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one - Physico-chemical Properties

Molecular Formula	C14H11BrO3
Molar Mass	307.14
Density	1.577g/cm³
Melting Point	176–177°C
Boling Point	481.7°C at 760 mmHg
Flash Point	245.1°C
Vapor Presure	6.64E-10mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.663

2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one - Introduction

2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone is an organic compound with the chemical formula C14H11BrO3.

Nature:
-Appearance: White crystalline solid
-melting point: about 120-122 ℃
-Solubility: Soluble in ethanol, dichloromethane and chloroform, slightly soluble in water

Use:
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone can be used in organic synthesis reactions and drug synthesis. It is an important intermediate for the synthesis of biologically active compounds, such as drugs, dyes and pesticides.

Method:
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone can be synthesized using benzoic acid as the starting material:
1. First, benzoic acid is reacted with brominated sulfoxide to obtain 4-bromobenzoic acid;
2. then, 2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl) acetic acid is prepared by esterification of 4-bromobenzoic acid and 2,4-dihydroxybenzoic acid;
3. Finally, 2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl) acetic acid was converted to 2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone by an acid-catalyzed transesterification reaction.

Safety Information:
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone is less toxic, but as an organic compound, it still needs to follow the safe handling of chemicals. When in use, wear appropriate personal protective equipment to avoid contact with skin and eyes. At the same time, a well-ventilated workplace should be maintained to avoid inhalation of its vapors. In case of accidental contact or inhalation, rinse immediately with water and seek medical help.

Last Update：2024-04-09 21:11:58