Name | 2-Acetamidofluorene |
Synonyms | Acetamidofluorene 2-Acetamidofluorene N-(2-Fluorenyl)acetamide N-(9H-fluoren-2-yl)acetamide 2-(9H-fluoren-2-yl)acetamide |
CAS | 53-96-3 |
EINECS | 200-188-6 |
InChI | InChI=1/C15H13NO/c16-15(17)8-10-5-6-14-12(7-10)9-11-3-1-2-4-13(11)14/h1-7H,8-9H2,(H2,16,17) |
Molecular Formula | C15H13NO |
Molar Mass | 223.27 |
Density | 1.227g/cm3 |
Melting Point | 192-196℃ |
Boling Point | 471.2°C at 760 mmHg |
Flash Point | 238.8°C |
Water Solubility | 0.000529 g/100 mL |
Vapor Presure | 4.73E-09mmHg at 25°C |
Appearance | Morphological Crystalline Powder, color off-white to tan |
pKa | 14.89±0.20(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.656 |
MDL | MFCD00001116 |
Physical and Chemical Properties | EPA Chemical Information 2-Acetylaminofluorene (53-96-3) |
Use | Genotoxic carcinogen, used to make the liver of mice carcinogenic, when oxidized by cytochrome CYP1A2 N-in the liver, 2-AAF is embedded in DNA, resulting in liver and bladder tumors. |
Hazard Symbols | T - Toxic |
Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R46 - May cause heritable genetic damage |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
RTECS | AB9450000 |
HS Code | 2924 29 70 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | Acute oral LD50 for mice 1,020 mg/kg (quoted, RTECS, 1985). |
toxic substance data | 53-96-3(Hazardous Substances Data) |
solubility | Soluble in acetone, acetic acid, alcohol (Weast, 1986), glycols, and fat solvents (Windholz et al., 1983) |
Merck | 14,4157 |
BRN | 2807677 |