2-Bromo-4-(aminomethyl)thiazole

2-Bromo-4-(aminomethyl)thiazole - Names and Identifiers

Name	2-Bromo-4-(aminomethyl)thiazole
Synonyms	2-broMo-4-(aMinoMethyl)thiazole 4-Thiazolemethanamine, 2-bromo- 2-Bromo-4-(aminomethyl)thiazole
CAS	933749-24-7

2-Bromo-4-(aminomethyl)thiazole - Physico-chemical Properties

Molecular Formula	C4H5BrN2S
Molar Mass	193.06
Density	1.782±0.06 g/cm3(Predicted)
Boling Point	263.9±15.0 °C(Predicted)
pKa	7.02±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

2-Bromo-4-(aminomethyl)thiazole - Introduction

2-Bromo-4-(aminomethyl)thiazole is an organic compound with the chemical formula C5H6BrN2S. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 2-Bromo-4-(aminomethyl)thiazole is a colorless to pale yellow solid.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Melting point: about 70-71 degrees Celsius.

Use:
2-Bromo-4-(aminomethyl)thiazole can be used as an intermediate in organic synthesis, and has a wide range of applications in the fields of drugs, pesticides and dyes.

Method:
2-Bromo-4-(aminomethyl)thiazole can be prepared by the following steps:
1. with sodium bisulfate as catalyst, the reaction of thiazole and formaldehyde in methanol.
2. Hydrogen bromide is added to the reactant 4-methoxythiazolethiol, thereby obtaining 2-bromo-4-(methoxythio) thiazole.
3.2-bromo-4-(methoxythio) thiazole is then reacted with ammonia methanol to give 2-Bromo-4-(aminomethyl)thiazole.

Safety Information:

Last Update：2024-04-09 02:00:49