933749-24-7 - Names and Identifiers
933749-24-7 - Physico-chemical Properties
Molecular Formula | C4H5BrN2S
|
Molar Mass | 193.06 |
Density | 1.782±0.06 g/cm3(Predicted) |
Boling Point | 263.9±15.0 °C(Predicted) |
pKa | 7.02±0.29(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
933749-24-7 - Introduction
2-Bromo-4-(aminomethyl)thiazole is an organic compound with the chemical formula C5H6BrN2S. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Bromo-4-(aminomethyl)thiazole is a colorless to pale yellow solid.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Melting point: about 70-71 degrees Celsius.
Use:
2-Bromo-4-(aminomethyl)thiazole can be used as an intermediate in organic synthesis, and has a wide range of applications in the fields of drugs, pesticides and dyes.
Method:
2-Bromo-4-(aminomethyl)thiazole can be prepared by the following steps:
1. with sodium bisulfate as catalyst, the reaction of thiazole and formaldehyde in methanol.
2. Hydrogen bromide is added to the reactant 4-methoxythiazolethiol, thereby obtaining 2-bromo-4-(methoxythio) thiazole.
3.2-bromo-4-(methoxythio) thiazole is then reacted with ammonia methanol to give 2-Bromo-4-(aminomethyl)thiazole.
Safety Information:
Last Update:2024-04-09 02:00:49