2-氨基恶唑-4-羧酸乙酯

2-氨基恶唑-4-羧酸乙酯 - Names and Identifiers

Name	Ethyl 2-Aminooxazole-4-Carboxylate
Synonyms	ETHYL 2-AMINO-4-OXAZOLECARBOXYLATE Ethyl 2-Aminooxazole-4-Carboxylate Ethyl 2-Amino-4-oxazolecarboxylate Ethyl 2-amino-1,3-oxazole-4-carboxylate 2-AMinooxazole-4-carboxylate ethyl ester 4-Oxazolecarboxylicacid,2-amino-,ethylester 2-Amino-4-oxazolecarboxylic Acid Ethyl Ester 2-Aminooxazole-4-carboxylic acid ethyl ester 2-AMINOOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 2-Amino-oxazole-4-carboxylic acid ethyl ester 4-Oxazolecarboxylicacid,2-amino-,ethylester(9CI) 2-AMino-1,3-Isoxazole-4-Carboxylic Acid Ethylester
CAS	177760-52-0
InChI	InChI=1/C6H8N2O3/c1-2-10-5(9)4-3-11-6(7)8-4/h3H,2H2,1H3,(H2,7,8)
InChIKey	NBABLVASYFPOEV-UHFFFAOYSA-N

2-氨基恶唑-4-羧酸乙酯 - Physico-chemical Properties

Molecular Formula	C6H8N2O3
Molar Mass	156.14
Density	1.278±0.06 g/cm3(Predicted)
Melting Point	124-128
Boling Point	282.9±32.0 °C(Predicted)
Flash Point	124.918°C
Vapor Presure	0.003mmHg at 25°C
Appearance	Light brown solid
pKa	2.82±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.523
MDL	MFCD06659907
Physical and Chemical Properties	Storage Conditions: Keep Cold

2-氨基恶唑-4-羧酸乙酯 - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29349990
Hazard Note	Harmful/Irritant/Keep Cold
Hazard Class	IRRITANT

2-氨基恶唑-4-羧酸乙酯 - Introduction

Ethyl is an organic compound with the chemical formula C6H7N3O3. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Ethyl L for white crystalline powder solid.
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane, insoluble in water.
-Melting point: About 158-160 ° C.

Use:
- Ethyl L is mainly used as an intermediate for the synthesis of drugs, especially oxazoles and amides.
-It can also be used as a raw material for the synthesis of pesticides, such as insecticides, fungicides and herbicides.

Method:
-Generally, the synthesis of Ethyl L is completed through a four-step reaction.
1. Ethanone reacts with aminoethanol to obtain 2-aminoethanone by ketonation.
2. 2-aminoethanone reacts with formic acid and dichloromethane under alkaline conditions to generate ethyl 2-aminooxazole-4-carboxylate.
3. 2-Aminooxazole-4-carboxylic acid Ethyl ester generates Ethyl phenyl through hydrolysis reaction.
4. Finally, the final product was obtained by crystallization purification.

Safety Information:
The specific toxicity and harmfulness of-Ethyl L has not been fully determined, but it can be used as a potential organic compound and should be handled with caution.
-During use, you must follow relevant laboratory procedures and pay attention to personal protective measures, such as wearing gloves, protective glasses and respiratory protective equipment.
-If you accidentally touch or inhale the substance, wash the affected area immediately and seek medical advice.

Please note that the information provided here is for reference only. Please be cautious when using or handling the substance and operate according to specific experimental operations and safety regulations.

Last Update：2024-04-09 21:00:56