2-溴异丁酰胺
2-BROMO-2-METHYLPROPANAMIDE
CAS: 7462-74-0
Molecular Formula: C4H8BrNO
2-溴异丁酰胺 - Names and Identifiers
| Name | 2-BROMO-2-METHYLPROPANAMIDE |
| Synonyms | 2-Bromoisobutyramide 2-Bromo-2-methylpropiomide 2-BROMO-2-METHYLPROPANAMIDE 2-Bromo-2-methylpropionamide 2-Bromo-2,2-dimethylacetamide PropanaMide,2-broMo-2-Methyl- |
| CAS | 7462-74-0 |
| InChIKey | WTRIMJTZOOLIFZ-UHFFFAOYSA-N |
2-溴异丁酰胺 - Physico-chemical Properties
| Molecular Formula | C4H8BrNO |
| Molar Mass | 166.02 |
| Density | 1.4132 (rough estimate) |
| Melting Point | 145-149 °C |
| Boling Point | 240.0±23.0 °C(Predicted) |
| pKa | 14.79±0.50(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5500 (estimate) |
| MDL | MFCD08234837 |
2-溴异丁酰胺 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29241990 |
| Hazard Class | IRRITANT |
| Packing Group | Ⅲ |
2-溴异丁酰胺 - Upstream Downstream Industry
| Raw Materials | 3-hydroxy-2,2-diMethyl-3-phenylpropanaMide 2-bromo-2-methylpropanenitrile 2-Bromoisobutyrylchloride Benzaldehyde 2-Bromoisobutyryl Bromide Ethyl 2-bromoisobutyrate |
2-溴异丁酰胺 - Introduction
2-BROMO-2-METHYLPROPANAMIDE is an organic compound with the chemical formula C5H10BrNO. The following is a description of the properties, uses, formulation and safety information of 2-bromo-2-methylpropylamide:
Nature:
-2-bromo-2-methylpropylamide is a colorless or light yellow liquid.
-It is soluble in water at room temperature.
-It has a pungent smell.
-It has a density of 1.454g/cm³.
-Its boiling point is 222-223°C.
Use:
-2-bromo-2-methylpropylamide is commonly used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize biologically active compounds.
-The compound has certain application value in the field of medicine and pesticide.
Method:
The synthesis method of 2-bromo-2-methylpropylamide can be carried out by the following steps:
1.2-methyl propionaldehyde reacts with bromoacetic acid to generate allyl alcohol bromide salt.
2. Under alkaline conditions, the bromide salt of allyl alcohol is dehydrated to generate 2-bromoisobutene.
3. Finally, 2-bromo-2-methylpropylamide is prepared by reacting 2-bromo-2-bromo-2-methylpropylamide with ammonia.
Safety Information:
-2-bromo-2-methylpropylamide is a corrosive substance, avoid contact with skin and eyes.
-During use, you should wear appropriate protective equipment, including gloves, protective glasses and laboratory coats.
-Avoid inhaling its vapor and ensure that it is operated in a well-ventilated place.
-Keep and dispose of the compound properly, following local regulations and guidelines.
Nature:
-2-bromo-2-methylpropylamide is a colorless or light yellow liquid.
-It is soluble in water at room temperature.
-It has a pungent smell.
-It has a density of 1.454g/cm³.
-Its boiling point is 222-223°C.
Use:
-2-bromo-2-methylpropylamide is commonly used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize biologically active compounds.
-The compound has certain application value in the field of medicine and pesticide.
Method:
The synthesis method of 2-bromo-2-methylpropylamide can be carried out by the following steps:
1.2-methyl propionaldehyde reacts with bromoacetic acid to generate allyl alcohol bromide salt.
2. Under alkaline conditions, the bromide salt of allyl alcohol is dehydrated to generate 2-bromoisobutene.
3. Finally, 2-bromo-2-methylpropylamide is prepared by reacting 2-bromo-2-bromo-2-methylpropylamide with ammonia.
Safety Information:
-2-bromo-2-methylpropylamide is a corrosive substance, avoid contact with skin and eyes.
-During use, you should wear appropriate protective equipment, including gloves, protective glasses and laboratory coats.
-Avoid inhaling its vapor and ensure that it is operated in a well-ventilated place.
-Keep and dispose of the compound properly, following local regulations and guidelines.
Last Update：2024-04-09 21:00:56
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View History
Raw Materials for 2-溴异丁酰胺
3-hydroxy-2,2-diMethyl-3-phenylpropanaMide
2-bromo-2-methylpropanenitrile
2-Bromoisobutyrylchloride
Benzaldehyde
2-Bromoisobutyryl Bromide
Ethyl 2-bromoisobutyrate
2-bromo-2-methylpropanenitrile
2-Bromoisobutyrylchloride
Benzaldehyde
2-Bromoisobutyryl Bromide
Ethyl 2-bromoisobutyrate