2369-37-1 - Names and Identifiers
2369-37-1 - Physico-chemical Properties
Molecular Formula | C6H3Br2F
|
Molar Mass | 253.89 |
Density | 2.014 |
Melting Point | 69℃ |
Boling Point | 220℃ |
Flash Point | 87℃ |
Refractive Index | 1.5780-1.5820 |
2369-37-1 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Note | Irritant |
2369-37-1 - Introduction
1,2-dibromo-4-fluorobenzene is an organic compound with the chemical formula C6H3Br2F. It is a white crystalline solid, insoluble in water at room temperature. The following is a detailed description of the nature, use, preparation and safety information:
Nature:
1,2-dibromo-4-fluorobenzene has a melting point of about 64-65 ° C and a boiling point of about 230-232 ° C. It has a density of 2.08g/cm³. It has a strong pungent odor. This compound is not uniform in electron density, resulting in increased electronegativity of bromine atoms and fluorine atoms, thus showing electron scattering with a lower resonance absorption frequency.
Use:
1,2-dibromo-4-fluorobenzene, as a reagent and intermediate of organic synthesis, is widely used in pharmaceutical, chemical and pesticide fields. It can be used as a raw material for the synthesis of amide compounds, and can also be used for aromatic nuclear substitution reactions in organic synthesis reactions.
Method:
The preparation of 1,2-dibromo-4-fluorobenzene is usually produced by fluorinating bromobenzene to produce 1,2-diiodo-4-fluorobenzene, and then passed through cuprous chloride (CuCl) A catalyzed Sandmeyer reaction converts it to 1,2-dibromo-4-fluorobenzene.
Safety Information:
1,2-dibromo-4-fluorobenzene should avoid contact with oxidants and acids during transportation and storage to prevent dangerous reactions. In use, should take the necessary safety measures, such as wearing protective gloves, glasses and respirators. This compound should be kept away from fire and high temperatures, and avoid inhalation, ingestion, or skin contact. Observe locally prescribed safe operating procedures during handling or disposal.
Last Update:2024-04-10 22:29:15