2375541-45-8
Autogramin-2
CAS: 2375541-45-8
Molecular Formula: C21H27N3O4S
2375541-45-8 - Names and Identifiers
2375541-45-8 - Physico-chemical Properties
| Molecular Formula | C21H27N3O4S |
| Molar Mass | 417.52 |
| Density | 1.252±0.06 g/cm3(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | solid |
| Color | Off-white |
| pKa | 7.59±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| Use | Autogramin-2 potently inhibits autophagy induced by either starvation (IC50=0.27 μM) or mTORC1 inhibition (Rapamycin; IC50=0.14 μM). |
2375541-45-8 - Reference
| Reference Show more | [1]. Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720. |
2375541-45-8 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.395 ml | 11.975 ml | 23.951 ml |
| 5 mM | 0.479 ml | 2.395 ml | 4.79 ml |
| 10 mM | 0.24 ml | 1.198 ml | 2.395 ml |
| 5 mM | 0.048 ml | 0.24 ml | 0.479 ml |
Last Update：2024-01-02 23:10:35
2375541-45-8 - Reference Information
| biological activity | Autogramin-2 effectively inhibits starvation-induced autophagy with an IC50 of 0.27 μm. Autogramin-2 also inhibited the autophagy induced by Rapamycin (by inhibiting mTORC1) with an IC50 of 0.14 μm. |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: Autogramin-2 Visit Supplier Webpage Request for quotationCAS: 2375541-45-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Autogramin-2 Visit Supplier Webpage Request for quotationCAS: 2375541-45-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History