239080-04-7
3-(Trifluoromethylthio)phenylacetic acid
CAS: 239080-04-7
Molecular Formula: C9H7F3O2S
239080-04-7 - Names and Identifiers
239080-04-7 - Physico-chemical Properties
| Molecular Formula | C9H7F3O2S |
| Molar Mass | 236.21 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Boling Point | 249.3±40.0 °C(Predicted) |
| Flash Point | 104.6°C |
| Vapor Presure | 0.0122mmHg at 25°C |
| pKa | 4.13±0.10(Predicted) |
| Refractive Index | 1.531 |
239080-04-7 - Introduction
3-(Trifluoromethylthio)phenylacetic acid is an organic compound with the chemical formula C9H7F3O2S. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-(Trifluoromethylthio)phenylacetic acid is white or light yellow solid.
-Solubility: Soluble in common organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
-Melting point: Its melting point is 60-62°C.
-Chemical properties: It is an acidic compound that can dissociate in water to generate the corresponding anionic form.
Use:
3-(Trifluoromethylthio)phenylacetic acid is commonly used as an optical, pharmaceutical, pesticide and pharmaceutical intermediate. It can be used to synthesize organic compounds with biological activity, such as antibacterial agents, anti-tumor drugs and pesticides.
Method:
3-(Trifluoromethylthio)phenylacetic acid is generally synthesized by the following steps:
1.3-nitrobenzene and sulfuryl chloride are reacted to obtain 3-nitrobenzene sulfuryl chloride.
2.3-nitrophenylthionyl chloride is reacted with trifluoromethyl mercaptan to obtain 3-(trifluoromethylthio) phenylthionyl chloride.
3. Finally, 3-(Trifluoromethylthio) phenylthionyl chloride is reacted with acetic acid to obtain the target product 3-(Trifluoromethylthio)phenylacetic acid.
Safety Information:
Note the following when using and handling 3-(Trifluoromethylthio)phenylacetic acid:
-Need to operate in a well-ventilated place to avoid breathing steam or dust.
-Wear appropriate protective equipment such as gloves, goggles and protective masks.
-Avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with water, if necessary, seek medical help.
-Avoid reaction with oxidants and strong acids, as hazardous substances may be produced or dangerous accidents may occur.
-Avoid contact with combustibles during storage and use to prevent fire and explosion.
Nature:
-Appearance: 3-(Trifluoromethylthio)phenylacetic acid is white or light yellow solid.
-Solubility: Soluble in common organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
-Melting point: Its melting point is 60-62°C.
-Chemical properties: It is an acidic compound that can dissociate in water to generate the corresponding anionic form.
Use:
3-(Trifluoromethylthio)phenylacetic acid is commonly used as an optical, pharmaceutical, pesticide and pharmaceutical intermediate. It can be used to synthesize organic compounds with biological activity, such as antibacterial agents, anti-tumor drugs and pesticides.
Method:
3-(Trifluoromethylthio)phenylacetic acid is generally synthesized by the following steps:
1.3-nitrobenzene and sulfuryl chloride are reacted to obtain 3-nitrobenzene sulfuryl chloride.
2.3-nitrophenylthionyl chloride is reacted with trifluoromethyl mercaptan to obtain 3-(trifluoromethylthio) phenylthionyl chloride.
3. Finally, 3-(Trifluoromethylthio) phenylthionyl chloride is reacted with acetic acid to obtain the target product 3-(Trifluoromethylthio)phenylacetic acid.
Safety Information:
Note the following when using and handling 3-(Trifluoromethylthio)phenylacetic acid:
-Need to operate in a well-ventilated place to avoid breathing steam or dust.
-Wear appropriate protective equipment such as gloves, goggles and protective masks.
-Avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with water, if necessary, seek medical help.
-Avoid reaction with oxidants and strong acids, as hazardous substances may be produced or dangerous accidents may occur.
-Avoid contact with combustibles during storage and use to prevent fire and explosion.
Last Update：2024-04-09 21:00:56
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