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25301-02-4

Triton

CAS: 25301-02-4

Molecular Formula: C17H28O3

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25301-02-4 - Names and Identifiers

Name Triton
Synonyms Triton
oxirane
alevaire
TYLOXAPOL
macrocyclon
4-(1,1,3,3-tetramethylbutyl)phenol
4-(1,1,3,3-tetramethylbutyl)-phenopolymerwithformaldehydeandoxirane
formaldehyde,polymerwithoxiraneand4-(1,1,3,3-tetramethylbutyl)phenol
CAS 25301-02-4
InChI InChI=1/C14H22O.C2H4O.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;1-2-3-1;1-2/h6-9,15H,10H2,1-5H3;1-2H2;1H2

25301-02-4 - Physico-chemical Properties

Molecular FormulaC17H28O3
Molar Mass280.402
Density1.1
Boling Point282.3°C at 760 mmHg
Flash Point148.3°C
Vapor Presure0.00198mmHg at 25°C
AppearanceMorphological Viscous Liquid
ColorClear to hazy yellow to amber
Merck13,9901
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
Physical and Chemical PropertiesBioactive Tyloxapol (Triton WR1339) is a non-ionic liquid polymer of alkyl aryl polyether alcohols, which is used as a surfactant during liquefaction and removes mucopurulent and bronchial and pulmonary secretions. It also inhibits plasma lipolytic activity, which breaks down triacylglycerol-rich lipoproteins.

25301-02-4 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany2
RTECSSM9750000
HS Code29222990

25301-02-4 - Upstream Downstream Industry

Raw MaterialsFormaldehyde
ETHYLENE OXIDE
Downstream Products1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

25301-02-4 - Nature

Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Last Update:2024-04-10 22:29:15

25301-02-4 - Uses and synthesis methods

Target

Target Value

lipoprotein lipase

in vitro studies

Tyloxapol is considered a safe stabilizer. In some studies, Tyloxapol has been reported to have toxic effects in epithelial cells and red blood cells, inducing apoptosis in RAW264.7 mouse phages and NIH/3T3 cells, and inducing lysis in human Jurkat T lymphocytes. However, these toxic effects do not reflect the in vivo effects of Tyloxapol, and they are rarely used alone in clinical practice.

In vivo studies

In rats, a single injection of 400 mg/kg tyloxapol by intravenous injection will produce three different stages in plasma lipids: relative to the basal level, there will be a rapid linear increase, then a relatively gentle linear increase, and finally a slow decrease. The treatment of Tyloxapol enhanced the pulmonary absorption of insulin and the absorption of inhaled insulin in a diabetic rat model. In diabetic rat models, the drug may significantly enhance the hypoglycemic effect of insulin perfused through the trachea, but does not change LDH activity.

Last Update:2024-04-09 22:09:11
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CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
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MedChemExpress (MCE)
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CAS: 25301-02-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Tyloxapol Visit Supplier Webpage Request for quotation
CAS: 25301-02-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Tyloxapol Visit Supplier Webpage Request for quotation
CAS: 25301-02-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
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View History
25301-02-4
盐酸间苯二胺
17334-08-6
突厥烯酮标准品
134419-41-3
屠锈胺
Raw Materials for 25301-02-4
Formaldehyde
ETHYLENE OXIDE
Downstream Products for 25301-02-4
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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