3,4-Difluoro-N-methoxy-N-methylbenzamide

3,4-Difluoro-N-methoxy-N-methylbenzamide - Names and Identifiers

Name	3,4-Difluoro-N-methoxy-N-methylbenzamide
Synonyms	3,4-Difluoro-N-methyl-N-methoxybenzamide 3,4-DIFLUORO-N-METHOXY-N-METHYLBENZAMIDE 3,4-Difluoro-N-methoxy-N-methylbenzamide Benzamide,3,4-difluoro-N-methoxy-N-methyl- benzamide, 3,4-difluoro-N-methoxy-N-methyl-
CAS	188345-25-7
InChI	InChI=1/C9H9F2NO2/c1-12(14-2)9(13)6-3-4-7(10)8(11)5-6/h3-5H,1-2H3

3,4-Difluoro-N-methoxy-N-methylbenzamide - Physico-chemical Properties

Molecular Formula	C9H9F2NO2
Molar Mass	201.17
Density	1.261g/cm³
Boling Point	315.1°C at 760 mmHg
Flash Point	144.4°C
Vapor Presure	0.000447mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.493

3,4-Difluoro-N-methoxy-N-methylbenzamide - Introduction

3, is an organic compound with the chemical formula C9H8F2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
3, is a white crystal solid, relatively stable at room temperature. It is flammable and can be dissolved in some organic solvents, such as methanol and dimethylformamide.

Use:
3, has a certain application value in drug synthesis. It can be used as a drug intermediate, commonly used in the synthesis of amides, ketones and acetylation products. Such compounds may have antitumor, antiviral and other activities in the pharmaceutical field.

Method:
3, preparation of the main use of chemical synthesis method. A commonly used method is to obtain 3,4-difluorobenzoyl chloride by the reaction of benzoyl chloride and cuprous fluoride, and then react with N-methoxy-N-methylamine under alkaline conditions, finally, the target product is obtained.

Safety Information:
3. It is relatively stable under normal operating conditions, but some safety matters still need to be paid attention. It is combustible and should avoid contact with fire. When operating, it is recommended to wear appropriate personal protective equipment, such as gloves, goggles and protective clothing. In addition, avoid breathing its gas, steam or mist, and ensure that the operating environment is well ventilated. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical attention. During storage and handling, relevant safety procedures should be followed to ensure the safe use of this compound.

Last Update：2024-04-09 20:52:54