3,5-Dichloropyridine-4-carboxaldehyde

3,5-Dichloropyridine-4-carboxaldehyde - Names and Identifiers

Name	3,5-dichloro-4-formyl pyridine
Synonyms	TIMTEC-BB SBB003785 3,5-DICHLOROISONICOTINALDEHYDE 3,5-dichloro-4-formyl pyridine 3,5-DICHLORO-4-FORMYL PYRIDINE 3,5-dichloroisonicotinaldehyde 3,5-dichloropyridine-4-carbaldehyde ,5-Dichloropyridine-4-carboxaldehyde 3,5-Dichloro-4-pyridinecarboxaldehyde 3,5-DICHLORO-4-PYRIDINECARBOXALDEHYDE 3,5-Dichloropyridine-4-carboxaldehyde 3,5-Dichloropyridine-4-carboxyaldehyde 3,5-DICHLOROPYRIDINE-4-CARBOXYALDEHYDE 4-pyridinecarboxaldehyde, 3,5-Dichloro- 3,5-Dichloropyridine-4-carboxaldehyde, 3,5-Dichloro-4-formylpyridine
CAS	136590-83-5
InChI	InChI=1/C6H3Cl2NO/c7-5-1-9-2-6(8)4(5)3-10/h1-3H
InChIKey	RBFNWOINNIOZKR-UHFFFAOYSA-N

3,5-Dichloropyridine-4-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C6H3Cl2NO
Molar Mass	176
Density	1.488±0.06 g/cm3(Predicted)
Melting Point	75-79 °C (lit.)
Boling Point	242.4±35.0 °C(Predicted)
Flash Point	100.4°C
Solubility	soluble in Methanol
Vapor Presure	0.0341mmHg at 25°C
Appearance	Solid
Color	White to Brown
pKa	-0.42±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.608
MDL	MFCD04039921
Physical and Chemical Properties	WGK Germany:3

3,5-Dichloropyridine-4-carboxaldehyde - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

3,5-Dichloropyridine-4-carboxaldehyde - Introduction

3,5-Dichloropyridine -4-carbaldehyde (3,5-Dichloro-4-formylpyriridine) is an organic compound with the chemical formula C- HCl-NO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3,5-dichloropyridine -4-carbaldehyde is a colorless to light yellow solid.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents such as methanol, ethanol and dimethylformamide (DMF).
-Melting point: Its melting point is about 73-77°C.
-Smelly: It has a special smell.

Use:
-3,5-dichloropyridine -4-formaldehyde is an important organic synthesis intermediate, commonly used in the synthesis of drugs, dyes, photosensitive materials and pesticides and other compounds.
-It can also be used as a ligand in palladium-catalyzed nucleophilic substitution reactions.

Preparation Method:
- 3,5-dichloropyridine -4-carbaldehyde can be obtained by reacting 3,5-dichloropyridine with formaldehyde under alkaline conditions. The reaction is typically carried out in an alcoholic solution of formaldehyde with the addition of a base such as sodium hydroxide (NaOH) or sodium carbonate (Na₂ CO₂).
-After the reaction is completed, the produced 3,5-dichloropyridine-4-carbaldehyde can be separated and extracted by crystallization or other purification methods.

Safety Information:
-3,5-Dichloropyridine-4-carboxaldehyde is an irritating compound that may cause irritation to the eyes, skin and respiratory tract.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, to avoid direct contact with skin and eyes.
-During operation and storage, avoid contact with oxidants and strong acids to prevent dangerous reactions.
-Due to its toxicity and irritation, please operate in a well-ventilated place and avoid inhaling its vapor.
-When handling this compound, please follow the relevant safety practices and guidelines.

Last Update：2024-04-09 21:04:16