3-(trifluoromethyl)phenylalanine - Names and Identifiers
3-(trifluoromethyl)phenylalanine - Physico-chemical Properties
Molecular Formula | C10H10F3NO2
|
Molar Mass | 233.19 |
Density | 1.364±0.06 g/cm3(Predicted) |
Melting Point | 216°C (dec.) |
Boling Point | 301.2±42.0 °C(Predicted) |
Flash Point | 135.9°C |
Vapor Presure | 0.000475mmHg at 25°C |
BRN | 7031717 |
pKa | 2.16±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.502 |
Physical and Chemical Properties | WGK Germany:3 |
3-(trifluoromethyl)phenylalanine - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
UN IDs | 2811 |
WGK Germany | 3 |
Hazard Note | Toxic |
Hazard Class | 6.1 |
3-(trifluoromethyl)phenylalanine - Introduction
L-3-trifluoromethylphenylalanine, chemical name L-3-(trifluoromethyl)phenylalanine, is an amino acid derivative. Its nature includes the following aspects:
1. Appearance: It is a colorless crystal or white crystalline powder.
2. Solubility: It has low solubility in water and is soluble in ethanol and acidic solution.
3. Stability: It is relatively stable at room temperature, but should avoid contact with strong oxidants.
The use of L-3-trifluoromethylphenylalanine is mainly concentrated in the field of medicine, including the following aspects:
1. Drug research: as an intermediate for the synthesis of small molecule compounds, it is used to develop drugs and participate in biological activity research.
2. peptide synthesis: as one of the important components of the synthetic peptide sequence, it is used to prepare peptide drugs with specific functions.
The main method for preparing L-3-trifluoromethylphenylalanine is through chemical synthesis. A common synthesis method is to use phenylacetone as a starting material and obtain the target product through a series of reactions.
Regarding its safety information, the following points should be noted:
1. When experimental operations are involved, necessary personal protective measures should be taken, including gloves, goggles and laboratory coats.
2. Avoid skin contact and inhalation of the product. In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
3. Store away from fire and oxidant, and keep the container sealed to prevent moisture.
4. The use of any chemicals requires strict compliance with relevant safety procedures and operating specifications.
Last Update:2024-04-10 22:41:03