L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE

L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE - Names and Identifiers

Name	3-TRIFLUOROMETHYL-L-PHENYLALANINE
Synonyms	H-PHE(M-CF3)-OH L-Phe(3-CF3)-OH H-Phe(3-CF_3)-OH H-PHE(3-CF 3)-OH RARECHEM BK PT 0133 L-3-Trifluoromethylphe L-3-TRIFLUOROMETHYLPHE H-L-PHE(3-TRIFLUOROMETHYL)-OH 3-(trifluoromethyl)phenylalanine L-3-TRIFLUOROMETHYLPHENYLALANINE 3-TRIFLUOROMETHYL-L-PHENYLALANINE 3-Trifluoromethyl-L-phenylalanine L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE
CAS	122839-48-9 14464-68-7
InChI	InChI=1/C10H10F3NO2/c11-10(12,13)7-3-1-2-6(4-7)5-8(14)9(15)16/h1-4,8H,5,14H2,(H,15,16)

L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE - Physico-chemical Properties

Molecular Formula	C10H10F3NO2
Molar Mass	233.19
Density	1.364±0.06 g/cm3(Predicted)
Melting Point	216°C (dec.)
Boling Point	301.2±42.0 °C(Predicted)
Flash Point	135.9°C
Vapor Presure	0.000475mmHg at 25°C
BRN	7031717
pKa	2.16±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.502
Physical and Chemical Properties	WGK Germany:3

L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
UN IDs	2811
WGK Germany	3
Hazard Note	Toxic
Hazard Class	6.1

L-3-(3-TRIFLUOROMETHYL)PHENYLALANINE - Introduction

L-3-trifluoromethylphenylalanine, chemical name L-3-(trifluoromethyl)phenylalanine, is an amino acid derivative. Its nature includes the following aspects:

1. Appearance: It is a colorless crystal or white crystalline powder.
2. Solubility: It has low solubility in water and is soluble in ethanol and acidic solution.
3. Stability: It is relatively stable at room temperature, but should avoid contact with strong oxidants.

The use of L-3-trifluoromethylphenylalanine is mainly concentrated in the field of medicine, including the following aspects:

1. Drug research: as an intermediate for the synthesis of small molecule compounds, it is used to develop drugs and participate in biological activity research.
2. peptide synthesis: as one of the important components of the synthetic peptide sequence, it is used to prepare peptide drugs with specific functions.

The main method for preparing L-3-trifluoromethylphenylalanine is through chemical synthesis. A common synthesis method is to use phenylacetone as a starting material and obtain the target product through a series of reactions.

Regarding its safety information, the following points should be noted:

1. When experimental operations are involved, necessary personal protective measures should be taken, including gloves, goggles and laboratory coats.
2. Avoid skin contact and inhalation of the product. In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
3. Store away from fire and oxidant, and keep the container sealed to prevent moisture.
4. The use of any chemicals requires strict compliance with relevant safety procedures and operating specifications.

Last Update：2024-04-10 22:41:03