3-Amino-6-bromo-quinolin-4-ol
6-BroMo-3-AMino-4-quinolinol
CAS: 1153094-27-9
Molecular Formula: C9H7BrN2O
3-Amino-6-bromo-quinolin-4-ol - Names and Identifiers
| Name | 6-BroMo-3-AMino-4-quinolinol |
| Synonyms | 6-BroMo-3-AMino-4-quinolinol 3-Amino-6-bromo-quinolin-4-ol 4-Quinolinol, 3-amino-6-bromo- |
| CAS | 1153094-27-9 |
3-Amino-6-bromo-quinolin-4-ol - Physico-chemical Properties
| Molecular Formula | C9H7BrN2O |
| Molar Mass | 239.07 |
| Density | 1.788±0.06 g/cm3(Predicted) |
| Boling Point | 403.3±45.0 °C(Predicted) |
| pKa | 2.88±0.50(Predicted) |
3-Amino-6-bromo-quinolin-4-ol - Introduction
6-Bromo-4-hydroxy-3-aminoquinoline is an organic compound with the chemical formula C9H7BrN2O. It is a fungal inoculant and fungicide. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 6-bromo-4-hydroxy-3-aminoquinoline is a white or light yellow solid
-Solubility: Its solubility in water is relatively low, but it has better solubility in organic solvents
-Melting point: Melting point is about 195-197°C
-Molecular weight: molecular weight is about 239.07g/mol
Use:
-Pesticide: 6-Bromo-4-hydroxy-3-aminoquinoline can be used as a fungicide, mainly used to control crop diseases, such as potato late blight, banana anthracnose, etc.
-Fungal inoculant: It can also be used to promote the reproduction and growth of fungi, and has certain application value for the study of mycology
Method:
The preparation of 6-bromo-4-hydroxy-3-aminoquinoline can be achieved by the following steps:
1. the reaction of 2-amino -5-bromopyridine and sodium nitrite to generate zinc salt nitroso acid under alkaline conditions.
2. Then the zinc salt nitroso acid reacts with p-phenylenediamine to generate 6-bromo -4-hydroxy -2-nitroquinoline.
3. Finally, 2-nitroquinoline was reacted with sodium sulfite to be reduced to the corresponding 6-bromo-4-hydroxy-3-aminoquinoline.
Safety Information:
-Since 6-bromo-4-hydroxy-3-aminoquinoline is an organic compound, care should be taken to prevent contact with skin, eyes and mucous membranes. Avoid inhaling dust or gas.
-When handling or storing the compound, it should be carried out in strict accordance with relevant safety procedures to ensure appropriate ventilation conditions and the use of personal protective equipment.
-If ingested or exposed to this compound, seek medical advice immediately and bring the packaging or label.
Nature:
-Appearance: 6-bromo-4-hydroxy-3-aminoquinoline is a white or light yellow solid
-Solubility: Its solubility in water is relatively low, but it has better solubility in organic solvents
-Melting point: Melting point is about 195-197°C
-Molecular weight: molecular weight is about 239.07g/mol
Use:
-Pesticide: 6-Bromo-4-hydroxy-3-aminoquinoline can be used as a fungicide, mainly used to control crop diseases, such as potato late blight, banana anthracnose, etc.
-Fungal inoculant: It can also be used to promote the reproduction and growth of fungi, and has certain application value for the study of mycology
Method:
The preparation of 6-bromo-4-hydroxy-3-aminoquinoline can be achieved by the following steps:
1. the reaction of 2-amino -5-bromopyridine and sodium nitrite to generate zinc salt nitroso acid under alkaline conditions.
2. Then the zinc salt nitroso acid reacts with p-phenylenediamine to generate 6-bromo -4-hydroxy -2-nitroquinoline.
3. Finally, 2-nitroquinoline was reacted with sodium sulfite to be reduced to the corresponding 6-bromo-4-hydroxy-3-aminoquinoline.
Safety Information:
-Since 6-bromo-4-hydroxy-3-aminoquinoline is an organic compound, care should be taken to prevent contact with skin, eyes and mucous membranes. Avoid inhaling dust or gas.
-When handling or storing the compound, it should be carried out in strict accordance with relevant safety procedures to ensure appropriate ventilation conditions and the use of personal protective equipment.
-If ingested or exposed to this compound, seek medical advice immediately and bring the packaging or label.
Last Update：2024-04-10 22:29:15
