3-CHLORO-1-PHENYL-PROPANONE
3'-Chloropropiophenone
CAS: 34841-35-5
Molecular Formula: C9H9ClO
3-CHLORO-1-PHENYL-PROPANONE - Names and Identifiers
| Name | 3'-Chloropropiophenone |
| Synonyms | MCPP M-CHLOROPROPIOPHENONE m-chlorophenylacetone 3'-Chloropropiophenone beta-Chloropropiophenone 3-CHLORO-1-PHENYL-PROPANONE 2-Chloroethyl phenyl ketone 3-CHLOROPHENYL ETHYL KETONE (3-CHLOROPHENYL)PROPAN-1-ONE 3-chloro-1-phenylpropan-1-one 3-Chloro-1-phenyl-1-propanone 1-(3-CHLOROPHENYL)-1-PROPANONE 1-(3-Chlorophenyl)-1-propanone 1-(3-chlorophenyl)propan-1-one 1-(4-chlorophenyl)propan-1-one 3-CHLOROPROPIOPHENONE M-CHLORO PROPIOPHENONE 3-Chloro-Propiophenone(M-ChloroProiophenone) |
| CAS | 34841-35-5 |
| EINECS | 252-242-3 |
| InChI | InChI=1/C9H9ClO/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6H,2H2,1H3 |
| InChIKey | PQWGFUFROKIJBO-UHFFFAOYSA-N |
3-CHLORO-1-PHENYL-PROPANONE - Physico-chemical Properties
| Molecular Formula | C9H9ClO |
| Molar Mass | 168.62 |
| Density | 1.1115 (rough estimate) |
| Melting Point | 45-47°C(lit.) |
| Boling Point | 124°C14mm Hg(lit.) |
| Flash Point | >230°F |
| Solubility | Soluble in methanol. |
| Vapor Presure | 0.0266mmHg at 25°C |
| Appearance | Bright yellow crystal |
| Color | White to light yellow |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5350 (estimate) |
| MDL | MFCD00009925 |
| Physical and Chemical Properties | Melting point 43-47°C boiling point 124°C (14 torr) |
| Use | For the synthesis of the drug bupropion |
3-CHLORO-1-PHENYL-PROPANONE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29147000 |
3-CHLORO-1-PHENYL-PROPANONE - Reference Information
| LogP | 3.041 |
| introduction | 3-chlorophenylacetone is a key intermediate for the synthesis of bupropion hydrochloride, dapoxetine and maravero. Ampropion hydrochloride is an antidepressant. It is a blocker for the absorption of serotonin and norepinephrine by weak neurons. It is suitable for patients with unknown efficacy of other depressive drugs or who cannot tolerate depression. At the same time, bupropion hydrochloride can also be used for the adjuvant treatment of smoking cessation, viral infection or sexual dysfunction. |
| application | 3 '-chlorophenylacetone is a key intermediate for the synthesis of bupropion hydrochloride, dpaoxetine and malavero. It can be mainly used in laboratory organic synthesis and chemical production. |
| preparation | 3 '-chlorophenylacetone is obtained by chlorination of phenylpropanone. the chemicals used in this method are: phenylpropanone, trichloride metal salt, solvent a, chlorine Cl2, where solvent a can dissolve both phenylpropanone and miscible trichloride, and its reaction equation is as follows: its operation steps are as follows: the first step is to add a proper amount of metal trichloride salt and solvent A to the reaction kettle, drop the phenylketone solution in the stirred state, introduce chlorine Cl2, perform chromatographic tracking of the reaction in the temperature range of 15~70 ℃, and stop the chlorination for about 6~10 hours; the second step, low temperature hydrolysis; the third step, water washing and stratification; the fourth step, decompression distillation to obtain the target crude product; the fifth step is to rectify the crude product at a temperature of about 170 ℃ to obtain a fine product with a content of 99.7% ~ 99.9%; the yield is 88% ~ 90%; |
| Uses | Used in the synthesis of the drug bupropion Organic synthesis and pharmaceutical synthesis intermediates can be used in the synthesis of bupropion. |
Last Update：2024-04-09 02:00:08
Supplier List
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 3'-Chloropropiophenone Request for quotation
CAS: 34841-35-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 34841-35-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Product Name: 3'-Chloropropiophenone Request for quotation
CAS: 34841-35-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 34841-35-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 3′-Chloropropiophenone Visit Supplier Webpage Request for quotation
CAS: 34841-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 34841-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 3'-Chloropropiophenone Request for quotation
CAS: 34841-35-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 34841-35-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: 3'-Chloropropiophenone Request for quotationCAS: 34841-35-5
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Product Name: 3'-Chloropropiophenone Request for quotation
CAS: 34841-35-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 34841-35-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 3′-Chloropropiophenone Visit Supplier Webpage Request for quotation
CAS: 34841-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 34841-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History