3-CHLORO-2-HYDROXY-5-FORMYLPYRIDINE

3-CHLORO-2-HYDROXY-5-FORMYLPYRIDINE - Names and Identifiers

Name	5-chloro-6-oxo-1H-pyridine-3-carbaldehyde
Synonyms	5-Chloro-6-hydroxynicotinaldehyde 3-Chloro-5-formyl-2-hydroxypyridine 3-CHLORO-2-HYDROXY-5-FORMYLPYRIDINE 5-chloro-6-oxo-1H-pyridine-3-carbaldehyde 5-CHLORO-6-HYDROXYPYRIDINE-3-CARBOXALDEHYDE 3-pyridinecarboxaldehyde, 5-chloro-6-hydroxy- 5-chloro-6-oxo-1,6-dihydropyridine-3-carbaldehyde 5-Chloro-1,6-dihydro-6-oxo-3-pyridinecarboxaldehyde 3-Pyridinecarboxaldehyde, 5-chloro-1,6-dihydro-6-oxo-
CAS	627501-18-2
InChI	InChI=1/C6H4ClNO2/c7-5-1-4(3-9)2-8-6(5)10/h1-3H,(H,8,10)

3-CHLORO-2-HYDROXY-5-FORMYLPYRIDINE - Physico-chemical Properties

Molecular Formula	C6H4ClNO2
Molar Mass	157.55
Density	1.43
Melting Point	255～257℃
Boling Point	303.2°C at 760 mmHg
Flash Point	137.2°C
Vapor Presure	0.000944mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.573

3-CHLORO-2-HYDROXY-5-FORMYLPYRIDINE - Introduction

It is an organic compound. Its structure contains a chlorine atom, a hydroxyl group and an aldehyde group. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow crystalline solid.
-Melting point: about 126-130 ℃.
-Boiling point: about 348 ℃.
-Density: about 1.39g/cm³.
-Solubility: low solubility in water, and in organic solvents such as ethanol, ether and methylene chloride more easily dissolved.

Use:
-and can be used as reagents and intermediates in organic synthesis.
-It is commonly used in the synthesis of compounds containing pyridine structure, such as drugs, pesticides, dyes and functional materials.

Preparation Method:
-It can be prepared by a series of reactions to carboxylic acids or ketones.
-A commonly used synthesis method is to react 3-chloro-5-cyanopyridine with hydrated calcium sodium oxide to obtain 2-hydroxy-3-chloro-5-pyridinecarbonitrile, which is then subjected to aldol reaction to obtain the target product.

Safety Information:
-It is an organic compound and has a certain degree of danger. Use should follow the safety procedures.
-For specific safety information, refer to the relevant MSDS or consult a professional body.

Last Update：2024-04-09 02:00:47