5-chloro-6-oxo-1,6-dihydropyridine-3-carbaldehyde - Names and Identifiers
5-chloro-6-oxo-1,6-dihydropyridine-3-carbaldehyde - Physico-chemical Properties
Molecular Formula | C6H4ClNO2
|
Molar Mass | 157.55 |
Density | 1.43 |
Melting Point | 255~257℃ |
Boling Point | 303.2°C at 760 mmHg |
Flash Point | 137.2°C |
Vapor Presure | 0.000944mmHg at 25°C |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.573 |
5-chloro-6-oxo-1,6-dihydropyridine-3-carbaldehyde - Introduction
It is an organic compound. Its structure contains a chlorine atom, a hydroxyl group and an aldehyde group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystalline solid.
-Melting point: about 126-130 ℃.
-Boiling point: about 348 ℃.
-Density: about 1.39g/cm³.
-Solubility: low solubility in water, and in organic solvents such as ethanol, ether and methylene chloride more easily dissolved.
Use:
-and can be used as reagents and intermediates in organic synthesis.
-It is commonly used in the synthesis of compounds containing pyridine structure, such as drugs, pesticides, dyes and functional materials.
Preparation Method:
-It can be prepared by a series of reactions to carboxylic acids or ketones.
-A commonly used synthesis method is to react 3-chloro-5-cyanopyridine with hydrated calcium sodium oxide to obtain 2-hydroxy-3-chloro-5-pyridinecarbonitrile, which is then subjected to aldol reaction to obtain the target product.
Safety Information:
-It is an organic compound and has a certain degree of danger. Use should follow the safety procedures.
-For specific safety information, refer to the relevant MSDS or consult a professional body.
Last Update:2024-04-09 02:00:47