3-Chloro-6-iodopyridazine - Names and Identifiers
3-Chloro-6-iodopyridazine - Physico-chemical Properties
Molecular Formula | C4H2ClIN2
|
Molar Mass | 240.43 |
Density | 2.187±0.06 g/cm3(Predicted) |
Melting Point | 118-120° |
Boling Point | 327.7±22.0 °C(Predicted) |
Flash Point | 151.991°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0mmHg at 25°C |
Appearance | Crystalline powder |
pKa | -1.18±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.653 |
MDL | MFCD08275187 |
3-Chloro-6-iodopyridazine - Risk and Safety
3-Chloro-6-iodopyridazine - Introduction
3-Chloro-6-iodopyridazine is an organic compound with the chemical formula C5H2ClIN2. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 3-Chloro-6-iodopyridazine is a white crystalline solid.
2. Solubility: It is almost insoluble in water, but can be dissolved in organic solvents (such as ethanol, acetone, benzene, etc.).
Use:
1. Chemical research: 3-chloro-6-iodopyridazine, as an important organic synthesis intermediate, is widely used in organic synthesis reactions, such as catalyst, zinc-iodine exchange reaction, etc.
2. Drug research: It is also used in drug research and can be used as a precursor for synthetic drugs.
Preparation Method:
3-chloro-6-iodopyridazine is generally prepared by reacting 2-nitro-5-phosgene pyridazine with sodium nitrite, followed by chlorination and iodination. The specific synthesis method needs to be carried out under laboratory conditions.
Safety Information:
1. 3-Chloro-6-iodopyridazine should be kept away from fire sources and oxidizing agents.
2. When in contact with skin, eyes or by taking, rinse immediately with plenty of water for at least 15 minutes and seek medical help.
3. When using and storing, please follow all safe operating procedures and ensure that the operation is carried out in a well-ventilated area.
4. Follow local national laws and regulations and laboratory operating guidelines to properly handle and dispose of waste and chemicals.
Last Update:2024-04-09 15:17:51