3-亚联氨基吲哚啉-2-酮
3-hydrazino-2H-indol-2-one
CAS: 2365-44-8
Molecular Formula: C8H7N3O
3-亚联氨基吲哚啉-2-酮 - Names and Identifiers
| Name | 3-hydrazino-2H-indol-2-one |
| Synonyms | Sunitinib Impurity 57 3-hydrazinylindol-2-one 3-Hydrazonoindolin-2-one 3-hydrazino-2H-indol-2-one 3-Hydrazono-1,3-dihydro-2H-indol-2-one |
| CAS | 2365-44-8 |
| InChI | InChI=1/C8H7N3O/c9-11-7-5-3-1-2-4-6(5)10-8(7)12/h1-4H,9H2,(H,10,11,12) |
3-亚联氨基吲哚啉-2-酮 - Physico-chemical Properties
| Molecular Formula | C8H7N3O |
| Molar Mass | 161.16 |
| Density | 1.49±0.1 g/cm3(Predicted) |
| Melting Point | 237-238 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 424.8°C at 760 mmHg |
| Flash Point | 210.7°C |
| Vapor Presure | 2.01E-07mmHg at 25°C |
| pKa | 10.63±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.734 |
3-亚联氨基吲哚啉-2-酮 - Risk and Safety
| Hazard Class | IRRITANT |
3-亚联氨基吲哚啉-2-酮 - Introduction
It is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-chemical formula: C8H7N5O
-Molecular weight: 185.18g/mol
-Appearance: White crystal or crystalline powder
-Melting Point: 187-192 ℃
-Solubility: Slightly soluble in water, easily soluble in organic solvents such as ethanol and chloroform
Use:
-is an important organic synthesis intermediate that can be used to synthesize various organic compounds.
-It can be used to prepare fluorescent dyes, photosensitizers and biomarkers, etc.
Method: The synthesis of
-is obtained by the ammonolysis reaction of carbon dioxide. First, indole -2,3-one reacts with carbamate under basic conditions to produce the corresponding hydrazide intermediate, which is then subjected to oxidation and deprotection reactions to give the product.
Safety Information:
-is not currently classified as a substance that can cause acute or chronic toxicity.
-When handling or using, it is recommended to wear appropriate personal protective equipment, such as chemical goggles and gloves.
-When storing, it should be placed in a dry, dark and well-ventilated place, away from flammable materials and oxidants.
-If inhaled or exposed to the compound, clean the affected area promptly and seek medical help.
Nature:
-chemical formula: C8H7N5O
-Molecular weight: 185.18g/mol
-Appearance: White crystal or crystalline powder
-Melting Point: 187-192 ℃
-Solubility: Slightly soluble in water, easily soluble in organic solvents such as ethanol and chloroform
Use:
-is an important organic synthesis intermediate that can be used to synthesize various organic compounds.
-It can be used to prepare fluorescent dyes, photosensitizers and biomarkers, etc.
Method: The synthesis of
-is obtained by the ammonolysis reaction of carbon dioxide. First, indole -2,3-one reacts with carbamate under basic conditions to produce the corresponding hydrazide intermediate, which is then subjected to oxidation and deprotection reactions to give the product.
Safety Information:
-is not currently classified as a substance that can cause acute or chronic toxicity.
-When handling or using, it is recommended to wear appropriate personal protective equipment, such as chemical goggles and gloves.
-When storing, it should be placed in a dry, dark and well-ventilated place, away from flammable materials and oxidants.
-If inhaled or exposed to the compound, clean the affected area promptly and seek medical help.
Last Update：2024-04-10 22:29:15
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CAS: 2365-44-8
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CAS: 2365-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: 3-hydrazinylindol-2-one Visit Supplier Webpage Request for quotation
CAS: 2365-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 2365-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
3-亚联氨基吲哚啉-2-酮
5-氯-2-羟甲基苯并咪唑
TRIETHYLSILYL TRIFLUOROMETHANE
TOSLAB 823407
3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, [2-13C-1,3-15N]-
咪唑-1-乙醇,2-甲基-
(S)-3-((((9H-芴-9-基)甲氧基)羰基)氨基)-4-羟基丁酸叔丁酯
6-羟基己酸
2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺
去乙烯基环丙沙星盐酸盐
5-氯-2-羟甲基苯并咪唑
TRIETHYLSILYL TRIFLUOROMETHANE
TOSLAB 823407
3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, [2-13C-1,3-15N]-
咪唑-1-乙醇,2-甲基-
(S)-3-((((9H-芴-9-基)甲氧基)羰基)氨基)-4-羟基丁酸叔丁酯
6-羟基己酸
2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺
去乙烯基环丙沙星盐酸盐